156 
COMPTE RENDU OF THE 
manual friction, but no amendment was produced; on the contrary, 
the state of the animal became every minute more alarming. His 
noisy and panting respiration — protruding eyes — extreme weak- 
ness, which caused him to seek instinctively the support of the wall 
or stall — his frequent falls, bodily — 'the pallor of the mucous mem- 
branes — the insensibility of the pulse — the coldness of the skin, 
&c., — all announced the near approach of death, which took place 
about ten o’clock. 
A Post-mortem Examination was immediately made. The 
abdomen contained a quantity of reddish fluid, in the middle of 
Avhich the alimentary matters floated ; the whole surface of the 
peritoneum was strongly injected ; the stomach and large intestine 
contained a considerable quantity of food ; the mucous membranes, 
and especially that of the colon, were much congested ; on this 
latter small blackish specks were observable, in patches, which 
were neither more nor less than eschars, occasioned by contact with 
some ill-dissolved fragments of the antimony. Towards the mid- 
dle of the floating portion of the colon was a longitudinal rupture, 
about an inch and a half in extent, the edges of which were 
blackened by an ecchymotic filamentous infiltration. A little in front 
of this rupture, upon the same portion of the intestines, there was 
another rupture, about a couple of inches in length, of the serous 
and muscular tunics. The mucous membrane was here intact. 
Case II. — A dappled grey cabriolet mare, of moderate size, 
eight years old, belonging to Dr. G — , Rue St. Anne, Paris. 
This animal had been for the last fortnight troubled with an un- 
pleasant discharge from the right nostril, the glands under the jaw 
on the same side being considerably developed. The work of this 
mare was very fatiguing, and consisted in drawing a four-wheeled 
carriage through the streets of Paris nearly the whole day. 
State of the animal when brought to the hospital . — In good 
condition — coat dull, dry, and rough — nasal flux from the right 
side — a slight discharge of whitish flaky matter adhering to the 
alae of the nostril — tumefaction of the sublingual glands, which 
were hard and flattened, and adherent to the bone ; — the right 
eye was tearful and bleared ; — no sign of erosion or ulceration was 
yet apparent on the pituitary, whose hue was nearly natural. 
Diagnostic . — Chronic glanders in its earliest stage. 
On visiting the animal on the 16th of November, the day after 
it was brought to the hospital, the administration of 16 grammes 
of antimony combined with 30 grammes of opium in an electuary 
of honey and marshmallow powder was prescribed ; and the pupil 
to whose care this animal was confided was desired to let it fast 
before the administration of the medicine, and not to give it any 
food until four hours after. After the lapse of some hours the 
