ROYAL VETERINARY SCHOOL AT ALFORT, 1841 - 2 . 101 
dies, that do not always possess, to the same degree, as is well 
known, the property of transmitting themselves. 
That which adds to the truth of this observation is, that we 
have not seen in the interior of any establishment those frightful 
cases of transmission of glanders to the human being which, 
during two years, had so sadly terrified us. Finally, in the hos- 
pitals of Paris the cases of glanders in man, according to the 
accounts of the medical journals, have been less frequent than in 
former years, Although he attention of medical men has been 
more anxiously than ever directed to this point. 
There is another circumstance that attracted our attention 
this year, and w'hich corresponds with those just quoted. Acute 
glanders has evidently exercised on the economy of the animals 
that it attacked a less rapidly destructive influence than dur- 
ing the preceding years. During two years, those that were 
infected usually sunk under the disease, and died between the 
ninth or twentieth day. This year we have seen a great num- 
ber of horses on which the eruption of acute glanders was only 
accompanied for several days by a febrile affection, which, rapidly 
subsiding, permitted the full return of the digestive functions 
and of all the other apparent indications of health, without, how- 
ever, the real symptoms of glanders disappearing. This explains 
the circumstance that, notwithstanding the attack of so dreadful 
a disease, a very great number of horses that exhibited it were 
employed in different ways in the timber-yards of the fortifica- 
tions, where the police sanatory laws were not observed. 
A concluding fact corroborates the account that we have just 
given of the comparative benignity of acute glanders in the course 
of the last year. We have witnessed in our hospitals the spon- 
taneous cure of five horses affected with acute glanders perfectly 
characterized. 
A disease which exercises so great an influence on the public 
health, merits all our attention and all our study ; so, with the 
view of throwing some light on its history, we have continued 
the series of experiments begun two years ago. We have en- 
deavoured, by a succession of inoculations, to determine whether 
acute glanders loses its contagious property by reproduction ; 
and we have seen that, even in the seventh generation, the viru- 
lence was as active in its effects as when it proceeded from 
glanders spontaneously developed. 
We have tried whether the matter flowing from the nostril, 
and dried in the open air, long preserved its virulent properties; 
and we have seen, at the end of six weeks, the scabs proceeding 
from this desiccation dissolved in distilled water, and acute farcy 
produced by the operation. 
VOL. XVI. 
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