326 THE L/pTE EPIDEMIC DISEASE IN FRANCE. 
hair. Jaundice presently appeared, with loss of appetite, consti- 
pation, abortion, and, finally, death. 
The prognosis which is connected with the fall of these 
eschars is very uncertain, by reason of the diversity of the parts 
which are found consecutively affected ; for, besides the acci- 
dents of which we have just spoken, and after the simple cica- 
trisation had taken place for a greater or less space of time, 
periostoses and exostoses will form, even of the bone of the 
cannon, along which eschars are produced by the tendinous 
parts. 
The loss of the integument, as well as that of the transversal 
ligament, give place again to the deformity of the bone of the 
hoofs. Sometimes this horn is large, puckered, rugose, and 
padded. Its separating from the parts beneath forms several 
incomplete hoofs, adapting themselves to each other, and which, 
when they break, cause the animal to suffer dreadfully. At 
other times this horn is thin, slender, always rugose, brittle, and 
framed in some irregular way, almost like a ram’s horn. The 
separation of the sole has also its complications. Strange bodies 
may interpose between it and the living parts, and form puru- 
lent reservoirs, almost always placed towards the point of the 
hoof. Very often, also, gravel is found, which is implanted in the 
fleshy sole, or between the upper and under portions of the sole. 
In these cases there are sometimes, in certain feet, three or four 
layers of horn, one on the other. 
The diseases of the feet, which compel the cows to remain 
long lying down, lead to the wearing out and loss of the 
epidermis ; and as that often happens on the articulations, parti- 
cularly on the coxo-femoral, the ligamentous parts separate, and 
even the trochanter dies away. The articulation then opens, and 
the synovia escapes ; purulent reservoirs form round the bone of 
the femur, and the bones of the hip and of the tibia contain a 
great quantity of white, purulent, and infectious matter. 
When the cow drags herself on her knees, which frequently 
happens, the hair of this part falls off. The integument assumes 
the form of a considerable tumour, and inflammation of the 
articulation, generally connected with a purulent deposit, is 
observed. The inflammation increases, and the patient sinks 
either before or after the opening of the articulation. Loss of 
appetite, as well as diarrhoea, always precede this sad termi- 
nation. 
The disease may, without any known cause, be driven back 
on the articulation, and this, too often, is followed by lesions, 
generally mortal, as I have just described. 
