THE LATE EPIDEMIC DISEASE IN SWITZERLAND. 337 
to the parietes of the lungs, but to the vessels which run between 
the prolongations of them, and which are thus obstructed, partly by 
the coagulation of so much blood in the veins and arteries, and 
partly by the accumulation of phlegm in branches of the trachea. 
3. That the hepatization and hardening of the texture of the 
lungs is a consequence of the obstruction of the small vessels of 
that organ, and hence arises that extraordinary thickening of the 
parenchyma. 
4. That in the larger vessels wherein I have observed the 
process of obstruction, a small polypous or fibrinous concretion 
will be found, wherever the inflammation has been more than 
usually intense. This concretion becomes the focus around which 
the coagulation extends itself on every side. Each point of 
adhesion has always a centre of white fibrous matter. The* free 
coagulation is black. The arteries and veins of the lungs become 
obstructed in a similar manner. 
5. A similar process of coagulation takes place in the bronchii. 
A white jelly-like coagulation is first of all formed in them, 
which afterwards gradually hardens into lumps. These approach 
each other by degrees — become still harder — acquire a reddish 
hue from the admixture of a little exuded blood — obstruct the 
bronchi — attach themselves to the sides of the bronchi, and end 
by becoming incorporated with them. I am perfectly convinced 
that this is no plastic exudation of the mucous membrane, for 
the freshly coagulated matter floats about in the bronchi in cylin- 
drical forms, almost resembling dew-worms. 
As I have before said, it was on the 8th of October, 1840, that 
the existence of contagious pleuro-pneumonia was first observed 
in the village of Denezy. From that time the strictest regula- 
tions were adopted, in order to prevent all communication 
between the infected animals and those in the neighbourhood 
and the surrounding districts. About the time of the com- 
mencement of these regulations three cows were killed in one 
stable, all of which were found to have been infected. A few 
days afterwards the disease was observed to be breaking out in 
another stable. Orders were given that all the beasts in it 
should be slaughtered, and this was done on the 22d of October. 
Eight animals were destroyed, and on post-mortem examination 
all proved to be infected. On the same day, a cow in a third 
stable was observed to be ill : it was destroyed on the 19th of 
November, and found to be affected by the disease; two other 
beasts in the same stable were also destroyed, and found to be 
infected. Each stable was thoroughly cleansed, fumigated, and 
purified, after the animals had been destroyed, and no others 
were placed in it until the disease subsided. 
