THE LATE EPIDEMIC DISEASE IN SWITZERLAND. 339 
the diaphragm, the lobes of the lung, and chiefly the front one, 
the middle and smaller ones being less affected. In other animals, 
where the disease had gained more ground, numerous tuber- 
cles were formed, and they gradually softened, and collections 
of purulent fluid ensued. In most of them the pleura was 
thickly covered with plastic granulations. In a few, broad 
patches of a brown and blue colour were observed, which cor- 
responded with those parts of the lungs that had suffered most 
from hepatization. In some the lungs appeared to be larger 
than they are in healthy animals. 
The veterinary surgeon also stated that this disease ran its 
course very slowly, and frequently was not perceptible in the 
living animal until it had reached its height. 
I have examined some portions of lung taken from animals 
that seemed, while living, scarcely at all affected, and found that 
in all of them the alterations caused by contagious pleuro- 
pneumonia were more or less apparent. The changes uniformly 
appeared to be of recent date, and not one shewed any trace of 
previous inflammation of the chest, still less of false membranes. 
The prolongations between the lobes of the lungs were neither 
thickened nor filled with serum, as I had previously always 
found them. Around the inflamed parts the bronchi contained 
polypous concretions of a whitish red colour, externally mingled 
with blood. These concretions were seldom attached to the 
mucous membrane. In other parts the bronchi were simply 
coloured by a fibrous bloody mucus. 
The parenchyma of the diseased parts was marbled, of a dark 
red colour, filled with blood, and more or less hepatized. The 
red spots consisted of patches of a dark red brown colour (a 
simple collection of blood with hepatization), or of bright red 
(inflammation and red hepatization), or of rose colour verging 
into white (inflammation degenerating into white hepatization). 
This last species of hepatization appeared to me most pecu- 
liarly to appertain to contagious pleuro-pneumonia. The blood 
which presses into the parenchyma of the lungs becomes gradu- 
ally decomposed, and loses its globulous and colouring properties, 
while the white and the fibrine coagulate, remain adhering to the 
parenchyma, and gradually form a firm white mass. 
In my opinion the polypi in the bronchi arise from the same 
cause and in the same manner. 
Most of the arteries and veins contain blackish clots of blood, 
here and there tinged with other colours, which are elastic and 
not adherent to the sides of the bloodvessels. 
In one of the lungs the pneumonic disease had assumed a 
very peculiar character. The collection of blood was diversified 
