340 INOCULATION FOR THE MOUTH AND HOOF DISEASE. 
by spots of a dark reddish hue, and somewhat resembling ecchy- 
mosis, varying in size from that of the head of a pin to a hazel- 
nut. These spots united themselves at different points, and, in 
one flap, covered it completely with a dark brown collection 
of hyperemia. The centre point of this half hepatized lung was 
darker and more compact than any of the rest. This kind of 
pleuro-pneumonia differed entirely from all that I had previously 
had an opportunity of observing. 
When the cattle were slaughtered, the farmers and owners 
requested that orders might also be given to destroy the sheep 
and goats, and, as this request was seconded by the veterinary 
surgeon, the authorities granted it as a measure of precaution. 
Hence I was enabled to examine the lungs of fifteen sheep. Not 
any of them shewed traces of the pleuro-pneumonic change. 
In one a slight trace of chronic pneumonia, with formation of 
matter and tubercles, was found. Some contained isolated 
hard tubercles, which were just beginning to soften. In these 
latter I found two very extraordinary appearances. First, that 
the tubercles do not soften, as is commonly believed, but sup- 
purate. Many of them which had reached the size of a pea were 
carefully cut open. In the centre was found one or more glo- 
bules of a yellow hue among the greyish white substance of the 
tubercle. These globules, when pressed under the finger, turned 
into a yellow flowery substance resembling hardened matter. 
Secondly, several of these tubercles, when cut open, were 
found to contain not matter, but a small clot of blood which 
swam in the middle. This clot could be lifted up and taken out 
on the point of a needle. Most of the tubercles which con- 
tained this clot of blood were perfect and uninjured, and ad- 
hered firmly to the surrounding tissue. 
Magazine fur die Gesammte T hie rheilk unde, p. 4, 1842. 
ON INOCULATION FOR THE MOUTH AND HOOF 
DISEASE IN CATTLE AND SHEEP. 
By Professor Hertwig. 
Herr Schwep, veterinary surgeon in the district of 
Tennstadt, in his quarterly report for 1841, communicates some 
experiments on the inoculation of sheep for this disease, which I 
here copy, because they have been made on a larger number of 
animals than any others of the kind which have yet come to my 
knowledge. Herr Schwep says : — 
