EFFECTS OF MEDICINE ON HORSES. 
377 
fessor Coleman and my father — that he should take the sulphate 
of copper, in order that the effects of the medicine might be 
ascertained. He commenced with the dose of an ounce daily. 
On the day the fourth dose was administered the horse was 
violently seized with purgation, at the same time expressing 
nausea and occasional griping pains, and bursting out into 
profuse sweats. The medicine was discontinued, and all the 
symptoms of pain and danger ceased, and the animal once 
more recovered his former state of health, although, in the 
end, the glanders proved fatal to him. 
Case II. — A bay gelding, having chronic farcy, in an ad- 
vanced stage, in one hind extremity, which was now in a state 
of extreme tension and suppuration, and was occasioning a great 
deal of uneasiness, had the actual cautery applied to his diseased 
limb, in a transverse direction, with a view of intersecting the 
absorbent vessels, and thus cutting off the communication be- 
tween the sound and diseased parts. But this operation had 
not been performed many days before fresh attacks of the 
absorbents appeared in various parts of the body. The case 
now becoming desperate, my father felt desirous to make trial of 
“ a new remedy,” one that had been “ much lauded by a 
modern practitioner as infallible this was the sulphate of cop- 
per. It was administered in half-ounce doses for eight succes- 
sive days, not only without benefit, but with the accession and 
rapid progress of glanders during its operation. My father 
expected to have found the stomach and intestines inflamed by 
the copper ; but they proved totally free from alteration. 
Case III. — In June 1801, a horse came under my father’s 
care, for treatment for farcy combined with glanders. Neither 
of the diseases having made much progress, it was thought 
advisable to give trial to the sulphate of copper, in divided 
doses. For the first eleven days one drachm of the medicine was 
given daily. On the four following days the dose was augmented 
to one drachm and a half, and this was given morning and 
evening, at the expiration of which period, the horse having lost 
his appetite and had some laxative effect produced on the 
bowels, the medicine was discontinued. Ten days afterwards, 
Mr. Coleman seeing the horse, was desirous that an experiment 
should be made on him with digitalis, the result of which shall 
be made known on a future occasion. 
Case IV. — There existing some difference of opinion be- 
tween Mr. Coleman and my father respecting the cathartic 
powers of the sulphate of copper, a fine chestnut horse, at the 
time under sentence to be destroyed on account of glanders, 
vol. xvi. 3 E 
