GLANDERS AND FARCY. 
449 
pale-coloured fluid, in a small quantity, from the internal ala of 
the nose. There was also effused a small quantity of serum from 
the internal wing of the right nostril, but the circumference of 
the punctures was not swollen. The pulse was increased to 48 
pulsations in a minute. 
On the I6th, at seven in the morning, no change was observed. 
In the evening the symptoms of inoculation were beginning to be 
marked . 
17 th . — At eight in the morning, the tumefaction of the punctures 
was increased. The tumours are more hot, harder, and more pain- 
ful. On the side of the upper lip, near the angle of the mouth, 
two elevated bands are observed, about an inch in thickness, 
elongated, irregular, and slightly painful. The left eyelids are 
greatly swollen, and the conjunctiva red. The air expired by 
the animal has a disagreeable odour, and the nostrils are smeared 
with fluid. The pulse is still natural and the animal eats well. 
18M. — At seven in the morning, the nodulated tumours of the 
right buttock are united by a band of smaller ones, very hot and 
very painful. There flows from the nostrils a fluid more deeply- 
coloured, and more abundant, than has yet been observed. We 
can now mark the rapid advance of the disease. 
19 th . — The circumference of the punctures in the nostrils 
appears more tumefied, especially on the left side. The respira- 
tion is more difficult, and all the tumefied parts are very painful. 
The animal eats little, and that with difficulty. 
20 th . — Exasperation of all the symptoms. The band on the 
upper lip is greatly increased, and very painful. All the tumours 
are circumscribed, and terminate abruptly, precisely like those 
peculiar to farcy. The animal, with much difficulty, is enabled to 
open her mouth to take food. 
21st . — The symptoms of injection are still more marked, and 
the local pain greatly increased. The disease now proceeded steadily 
in its course for some days ; and, on the twenty-first day from 
the period of inoculation, the unfortunate animal was destroyed, 
after having presented all the characteristics of glanders and 
farcy. After death, the diseased portions of the horse were ex- 
cised, and, on careful examination, found to be precisely the 
same as those commonly observed in glandered animals. 
Several useful inferences may be drawn from the foregoing de- 
tails. In the first place, it proves, beyond a doubt, that it was 
glanders of which the man died, for a horse, previously healthy, 
was impregnated with that disease by the inoculation of matter 
taken from Prost after death. It is well known that the horse 
usually takes the disease without being inoculated, namely, by 
contagion , as it is called ; but, until the foregoing inquiry was 
