GLANDERS IN THE HUMAN SUBJECT. 287 
tion of glandercd matter to the nasal linings, in picking, scratch- 
ing, or blowing that organ : — Corporal John Weils, aged 38, a. 
tali healthy-looking man, It) years in the corps, and never before 
on the doctor's list, on the 16th of April last was suddenly awa- 
kened from an unrefreshing sleep by rigors, headach, and great 
irritability of stomach. In hospital (at Cahir Barracks, Ireland) 
next morning, he complained, in addition, of severe continued 
pains, and stiffness in all his large joints, excessively aggravated 
on the slightest motion. These are the constant precursors of 
fatal acute glanders and farcy in the horse. On inquiry, it ap- 
peared that he had sol& charge of a glandered horse for some 
time previous, which had been destroyed on the evening of his 
attack ; and that he had exerted himself much in cutting up the 
carcass. But these circumstances not then creating the least 
suspicion, his complaint was considered to be severe acute rheu- 
matism. However, two days after admission, finding that his 
constitution was no longer able to bear the active treatment em- 
ployed, Dr. Home and myself became truly alarmed at the un- 
conquerable violence and novelty of the disease. 
The pain, night and day, became excessive, particularly over 
the left shoulder, where the scapula was slightly tumefied, al- 
though not inflamed. Leeches applied over its entire surface, bled 
profusely for some hours, without relief; his sufferings continued 
unabated. On the 24th the tumour had a dark livid colour, and 
was so large as to resemble the shoulder of a man recently and 
severely punished. Similar tumefactions, but more circumscribed, 
were now observed on the legs, arms, and sacrum, and one over 
the left temple distorted the entire face. The right nostril was 
contracted, and gummed with an inspissated discharge; and he 
complained of constriction of the throat, with difficulty of swal- 
lowing cold liquors, but not warm ; the posterior fauces were 
much inflamed, and nearly of a purple hue. The suffering now 
baffled every effort to procure rest ; not even whilst in the warm 
bath had he a moment’s respite from pain. His thirst was great ; 
his excretions, urinary and alvine, were kept natural in every 
respect. On the 28th, several warty pistules were observed, re- 
sembling yaws, particularly over the neck and shoulders, and in- 
side the arms and thighs. Several of the tumours were now run- 
ning rapidly into gangrene, wholly unimpeded by tonics and an- 
tiseptics. Nature was at length exhausted, his countenance 
frightfully haggard and livid, his entire surface bathed in a cold 
clammy sweat, and of a pale leaden hue. He held out, in partial 
somnolency and low muttering delirium, until the 30th, when 
death released him from his misery, having been twelve days 
under treatment. 
Autopsy 18 hours after death . — The entire surface nearly co- 
