288 
GLANDERS IN THE HUMAN SUBJECT. 
vered with black gangrenous tumours, each surrounded by nume- 
rous small vesications, which, on cutting into them, were found 
to be merely elevations of the cuticle, filled with a dark violet- 
coloured inspissated lymph. A suspicion having been recently 
entertained that this disease had its origin in glanders, the ab- 
sorbents of each arm were first minutely examined, to their ter- 
mination in axillary glands. Those vessels, however, as well as 
the glands, were found in their natural state ; nor was there the 
slightest appearance of either absorbent, glandular, or cutaneous 
inflammation, or of any recent cicatrices, chopped or scratched 
fingers, or, in short, the slightest breach of integument, or abra- 
sion of skin, by which absorption of morbid matter into the sys- 
tem could have been facilitated. 
On removing the scalp, and thereby dividing the tumour al- 
ready specified, we observed, immediately over the left super- 
ciliary ridge, a cluster of tuberculated bodies, of various sizes, 
imbedded in a lamina of the cellular tissue, exterior to the pe- 
ricranium ; and our highly talented veterinary surgeon, Mr. 
Woodman, unhesitatingly recognized a strong resemblance be- 
tween these, and those found in the nasal linings of glandered 
horses after death. 
The brain was much more pale and soft than ordinary, with 
rather a larger proportion of fluid in the ventricles; the Schnei- 
derian membrane appeared throughout pale, thickened, and 
infiltrated ; and in the right frontal sinus was found another 
cluster of well-defined, ulcerated, glanderous tubercles. The 
posterior fauces were highly inflamed, and of a dark purple hue ; 
right tonsil ulcerated in patches ; but the thoracic and abdominal 
viscera were all perfectly healthy, except that the heart was 
rather pale and flabby. 
On removing the whole of the diseased mass from the sca- 
pula, that bone was observed nearly covered by a cluster of grey, 
circular tubercles, the whole composed of fine cellular tissue, 
enveloped in small cysts, and firmly attached to the periosteum, 
differing only in this respect from those found in the pericar- 
dium. (?) The tumours on the sacrum and extremities all ex- 
hibited each precisely the same crop of tubercles adhering to 
the periosteum underneath. All the muscles were blanched, 
flabby, and softened, and the cellular membrane was infiltrated 
with a yellow serosity. 
Lancet, Mai) 6, 1837. 
