GLANDERS IN THE HUMAN BEING. 
337 
nience, particularly in a chronic state ; but at other times they 
are large, painful, numerous, and rapid in their course. They 
are at first hard, but soon become soft, burst, and degenerate into 
foul ulcers, with abrupt edges, and of a pale glossy appearance. 
Lines of communication are generally observed between these 
tumours or ulcers, particularly when seated on the insides of the 
limbs : these lines are inflamed and enlarged absorbents. 
5. — I. Description of Glanders in the Human Sub- 
ject. — Dr. Elliotson remarks, that glanders may appear in the 
human subject in different forms: — 1st, In that of simple acute 
glanders ; the disease attacking the nasal cavities and adjoining 
parts. 2d, In that of acute farcy glanders; the malady ap- 
pearing in various parts in the form of small tumours, giving 
rise to foul ulcers, suppuration, &c. 3d, These varieties may 
exist separately, or they may be both produced at the same time, 
or the one may precede the other. 4th, Each of them may also 
occur in a chronic form, and in this form, also, may exist sepa- 
rately or be conjoined. That the acute true glanders and the 
farcy glanders are the same disease is proved by the fact, that 
the matter deposited in the tumours characterizing the latter, or 
that coming from the nostrils in the former, gives rise to either 
of these varieties, or to both conjoined ; or, in other words, that 
simple acute glanders may proceed from the matter of farcy, or 
from its own discharge, and that farcy glanders may arise from 
the discharge from the nostrils in simple acute glanders. 
6. — i. Simple acute glanders appears, to commence with rigors, 
headache, irritability of stomach, depression of spirits, prostra- 
tion of strength, stiffness and severe constant pain of the joints, 
aggravated by motion, and great thirst. The patient, moreover, 
complains of much heat about the nasal organ and windpipe, 
accompanied by a copious viscid discharge. The nose and sur- 
rounding parts become swollen, hot, excoriated, and of a bright 
red or livid colour; one or both eyes are inflamed, or completely 
closed ; a profuse tenacious mucus, at first of a deep yellow, but 
afterwards of a dark sanious appearance, exudes from one or both 
nostrils, sometimes, also, from the eyes ; and several hard phly- 
zaceous pustules appear on the nose and adjacent parts, and on 
the neck, trunk, arms, thighs, and legs. The temperature of 
the skin is increased, the pulse is remarkably frequent, soft, and 
weak or undulating ; the respiration rapid, weak, and shallow ; 
the tongue dry, rough, and brownish red ; thirst is unquench- 
able ; the stools are watery, or slimy and offensive ; the voice is 
weak, and the mind incoherent or wandering. Copious offensive 
sweats, a livid or gangrened state of the nose or of adjoining 
parts, delirium, tremors, and restlessness, are also observed ; 
