338 
GLANDERS IN THE HUMAN BEING. 
followed by sinking of all the vital powers, disappearance of the 
pulse, and death within a very few days : the fcetor from the dis- 
charges, and from the whole body, towards the close of the dis- 
ease, being insupportable. 
7. Upon inspection post-mortem, the morbid appearances, es- 
pecially those which are external, are greater on one side than on 
the other. The longs are engorged with dark fluid blood ; the 
bronchi are livid, congested, and partially filled with a dark 
frothy mucus ; the nostrils and frontal sinuses contain a glutin- 
ous matter of a brownish colour, and the lining membrane is 
studded with ulcerated white tubercules or granules ; irregular 
ulcers, or white circular chancres, sometimes also exist in the 
upper part of the air- passages ; purulent deposits are occasion- 
ally found in some of the internal viscera; and the mucous sur- 
face of the digestive canal is softened and discoloured at various 
points. White tubercular formations, resembling those found in 
the membrane of the nose, sometimes also exist in the mucous 
membrane of the large bowels. 
8. — ii. Acute Farcy Glanders seems to commence with severe 
pain in the joints and limbs, and with other symptoms attending 
the invasion of the other variety. Small tumours arise in dif- 
ferent parts of the body, but are more numerous on one side than 
on the other, and have a glossy red appearance, which soon 
changes to a dark brown. They also affect the head, or even 
the face, and chiefly on one side. They are painful, soon crack 
on the surface, and exude a thin acrid sanies: they vary in size, 
and are generally accompanied by phlyzaceous ulcers in different 
parts of the body. Perspiration is free, copious, and foetid ; and 
the stools are watery, offensive, and otherwise morbid. The 
fauces are injected, and of purplish hue; thirst is great ; the 
tongue foul, loaded, and dark coloured ; the pulse quick and 
easily compressed ; afterwards small, and scarcely perceptible ; 
and the other symptoms attending a fatal termination soon after- 
wards appear as in the preceding form. On inspection after 
death the tumours are found deeply seated. On removing the 
gangrenous integument covering them, a layer of brown glutin- 
ous matter is seen covering small white tubercules, having the 
same appearances as those found in the frontal sinuses, and nasal 
cavities, in acute simple glanders. These tubercules on the fore- 
head or scalp are generally connected with the pericranium ; but 
on the limbs with the fasciae. In some cases, on dividing the 
larger livid or gangrenous tumours, down to the bone, the mus- 
cles appear decomposed, are of a dark colour, exhale a peculiar 
foetid odour, and contain specks of a purulent matter, as it were, 
infiltrated through their substance. Underneath these muscles 
