039 
GLANDERS IN THE HUMAN BEING. 
clusters of circular grey tubercules are found, firmly attached to 
the periosteum, and resembling those that are more superficial, 
as in the pericranium, &c. The muscles generally, even those 
remote from the tumours, are blanched, flabby, or softened, and 
the cellular tissue is infiltrated with a yellow serum. The 
Schneiderian membrane, frontal sinuses, and parts adjoining, are 
sometimes thickened, or studded with white tubercules. The 
blood is dark, fluid, and decomposed ; and the heart flabby, and 
pale. 
9. When acute farcy is conjoined with acute glanders , the 
affection of the nares and respiratory organs, the phlyzaceous 
pustules around the nose and mouth, and the consequent foetid 
sanious discharge, and disorganization, are associated with the 
foregoing phenomena ; but the constitutional symptoms are not 
thereby otherwise changed, than in being aggravated, or rendered 
more malignant, or more rapid in their progress to dissolution. 
In such cases the morbid appearance of the nares, fauces, and 
respiratory surfaces attending the acute glanders, are superadded 
to those characterising acute farcy. 
10. iii. The Chronic Forms of Glanders . — Simple chronic 
glanders is confined chiefly to one nostril, and is characterised by 
a glutinous and very offensive discharge, the fcetor being pecu- 
liar, and remarkably disagreeable. There are itching, with a 
constant desire to blow' the nose, and a sensation of stuffing. In 
the slightest state of the disease, these may be the principal 
symptoms; but, in a more advanced stage, or in severer cases, 
there are pain between the eyes and down the nose, with suffu- 
sion of the eyes, and ulceration of the Schneiderian membrane, 
the discharge being copious, puriform, and sanious. These 
symptoms are usually preceded by shiverings, giddiness, and by 
weakness and pains of the limbs ; and are followed by more or 
less constitutional disturbance. As the disease proceeds, puru- 
lent collections form in different parts. There are, moreover, 
loss of appetite, nausea, swimming or pains of the head, occa- 
sional wanderings of the mind, pains in the back and limbs, 
thick, discoloured, or foetid urine, and slimy or otherwise morbid 
evacuations. From this state the patient may slowly recover, 
after an indefinite period, or may sink gradually, from prostration 
of all the vital powers, with appearances of contamination of the 
circulating and secreted fluids. 
11. Chronic farcy glanders are generally preceded and ac- 
companied by chills or rigors, and aching pains through the body 
and limbs, resembling rheumatism. Tumours gradually form 
about the face, trunk, and limbs ; these break, and give rise to 
an unhealthy discharge; and are attended and followed by 
