478 
THE EFFECTS OF IODINE IN GLANDERS. 
cavalry veterinary surgeon, wields one of the same weapons, 
and that which alone concerns us in the present inquiry ; but he 
occupies a very different ground. In 1832, he had to treat 
eighteen farcied horses. His favourite medicine was iodine, but 
he had great difficulty in giving it : some of his patients would not 
be forced, and the medicine, in the doses in which he was com- 
pelled to give it, was very expensive. It struck him, in the 
summer of 1834, that, as recommended by Professor Dupuy 
with regard to a great many other medicines, he would inject it 
into the veins. He did so by means of a tolerably large opening 
into the jugular, and the introduction of a small tube resembling 
a catheter. Although he had in the course of treatment many 
openings to make in the veins of each, and there was sometimes 
considerable difficulty in introducing the tube, he had only one 
case of phlebitis. 
He refers, as as pecimen of the rest, to L’Allegro, a Norman 
horse, that had been under treatment seven months, fof farcy, 
which had closely followed the insertion of setons in a case of 
intense pneumonia. On the 9th of July 1834, he received in the 
left jugular two drachms of iodine, dissolved in two ounces of 
alcohol ! The injection had scarcely been made ere the respira- 
tion became much disturbed ; it was short and frequent, and 
interrupted by a dry and convulsive cough, which did not en- 
tirely disappear during several days. The nostrils were dilated 
— the flanks convulsively heaving — indeed, it was dypsncea carried 
to its greatest extent. The dejections were frequent — the pulse 
irregular, frequent, hard, and embarrassed — the subcutaneous ves- 
sels, especially those of the face, were prominent — the conjunctiva 
injected — the countenance haggard — the staggering gait which 
was first evident was succeeded by a remarkable stiffness or 
immobility — the temperature of the body was irregular — partial 
sweats broke out — the pulsations of the heart were obscure, some- 
times intermittent, and a mucous rale was heard on the appli- 
cation of the ear to the windpipe. Six hours afterwards the 
wounds, and the little pus which they furnished, had a yellow 
tint, like that which is produced by iodine when applied to the 
skin — the expired air exhaled the odour of chlorine — there was 
much anxiety of countenance, and the animal refused all food. 
It was the same on the following day, only the animal ex- 
pressed much pain when the buttons that were considerably 
ulcerated were pressed. 
There was little change during four days, and then the 
appetite returned, and the tumours lost their newly acquired 
sensibility. On the 8th day, there was nothing by which the 
exhibition of the medicine could be recognized, and certainly no 
