THE EFFECTS OF IODINE IN GLANDERS. 479 
advantage had been obtained. A month afterwards no symp- 
toms of amendment appeared, and he was destroyed. 
On the 17th of June he injected into another horse with 
inveterate farcy one drachm of iodine, dissolved in two ounces 
of alcohol. There was immediate fulness and acceleration of 
the pulse, with dry, painful, and continual cough, that con- 
tinued some days. Encouraged on perceiving that the consti- 
tutional disturbance was now so slight, he selected twelve horses 
that had been many months submitted to the common treatment 
for farcy, but without the slightest good effect ; and he deter- 
mined that he would try on them the power of iodine injected 
into the veins. 
From the 19th to the 25th of June, one drachm of iodine 
dissolved in two ounces of alcohol was injected into the jugu- 
lar vein of these horses. 
From the 26th to the 30th, the injection was suspended. 
From the 1st to the 4th of July it was again administered — 
from the 5th to the 8th there was a respite, and from the 9th 
to the 17th the injection was resumed. In the whole, the injec- 
tion was repeated twenty times on each horse. 
After the injection, the animal usually appeared stupid — he 
staggered — seemed as if he were drunk, and sometimes fell 
down. The respiration was short and frequent, accompanied 
by painful and irregular cough — the pulse was strong and fre- 
quent — the countenance haggard — the pupil dilated — the sight 
impaired — the vessels of the face swollen — the dejections passed 
with pain and groaning — the skin was damp — there was fre- 
quent yawning and grinding of the teeth, and the expired breath 
had an odour of chlorine. Presently there came on a kind of 
fainting or stupor, which lasted a little while. At the expiration 
of an hour and a half after the injection of the medicine, all 
this had passed away— the gaiety and the appetite returned, 
and, indeed, the horse ate with a kind of voracity. In some of 
the animals, many of these effects of the medicine were not 
observed — in others, they were exceedingly intense ; but in all 
of them there was considerable cough. 
At the commencement of the experiment an intractable horse 
fell, some seconds after the injection, struck his head on the 
edge of the manger, and died in a moment. The man who 
held this horse was an awkward fellow. 
The principal post-mortem lesion was slight ecchymosis on 
the posterior wall of the right ventricle. 
At the same time, two horses belonging to officers of the 
regiment became farcied — the one, in consequence of setons in 
the chest — the other had the stump of the tail entirely covered 
