592 GLANDERS FOLLOWING THE BITE OF A DOG. 
D uring the next five days lie was slow and dull at his work, 
and several times, as the proprietor afterwards told me, he refused 
to proceed, or to obey the intimations of the whip,— a thing 
which he had never done before. 
On the 25th I was sent for again to Wolffckansheim. The 
wounds had on the preceding evening spontaneously re-opened, 
and an ichorous and fetid pus ran from them. To this succeeded 
ptyalism, loss of appetite, vague inquietudes, and such a deter- 
mination to bite, and especially his master, that neither he nor 
his children dared to enter the stable again during the life of the 
animal. I cleaned the wound, and bathed it with a decoction of 
wild roses, mixed with honey and vinegar ; and at 11 o’clock, 
there being considerable enlargement between the jaws, and the 
conjunctival and pituitary membranes being inflamed, I bled him 
copiously, and ordered him proper cooling drinks. 
26th . — There is slight trismus, and the wounds are livid and 
fungous. Apply calcined alum to them, and camphorated lini- 
ment over the head generally. 
27th . — The trismus has disappeared, and he eats some bits of 
hay which are offered to him, but after slight mastication he 
drops them from his mouth. A little white water was then given 
him to drink, but the difficulty and pain which he had in swal- 
lowing the fluid, plainly indicated a constriction of the throat 
which prevented deglutition. The wounds are looking better. 
Apply more of the alum. 
28th . — The horse is tranquil, the general enlargement of the 
channel between the jaws has subsided, but there remains a 
large gland, adherent and tender, near the angle of the left jaw. 
There is also discharge from the left nostril, consisting of thick 
pus, with some sanious fluid. Dress the wounds as before — 
inject into the nostrils soothing fumigations. Towards evening 
I remarked the rapidly increasing blue colour of the nasal mem- 
brane. 
29th . — The discharge was now in the highest degree offensive,* 
the pituitary membrane was sphacelated at its inferior part, 
and above I remarked numerous ulcers, some of which perforat- 
ed the cartilaginous septum. The wounds were almost healed. 
I endeavoured to prevail on the proprietor to destroy the horse ; 
but on his refusal I obtained an order from the mayor that it 
should be done. I regret that my occupations did not permit 
me to be present at the post-mortem examination of the animal. 
The acute glanders which so plainly existed in this horse, 
was it the result of or connected with any rabid reaction ? or may 
it be traced to the irritation which then existed in the lymphatic 
ganglions and the other part of the head ? 
