ON THE PRODUCTION OF GLANDERS. 
223 
mentation. Placed in contact with matter capable of feeding it, 
the glandered principle assimilates it, and greatly hastens the 
organic decompositions. In fact, chemical analysis seems to de- 
monstrate that the exhalation of carbonic acid is much more consi- 
derable in an animal under the influence of glandered fermentation 
than, if I may be allowed the expression, in an animal in health. 
Such is the theory : let us now consider the facts. 
X. Experience has shewn, and every day still shews, that in- 
cessant work, without rest, such as is exacted of horses in certain 
undertakings, is one of the most frequent causes of glanders, acute 
and chronic, but principally of acute. No discussion, I should 
imagine, will arise on this point, it being an acknowledged fact 
set forth every year in the comptes rendus of the Alfort School. 
It is no less certain that in the greatest number of cases, whenever 
a horse becomes glandered from over work, it falls greatly off in 
condition before the disease makes its appearance ; a fact which 
accords with the great exhalation of carbonic acid and water, the 
fatal consequences of the activity of the respiratory and circulatory 
functions. 
On the other hand, whenever glanders has declared itself, the 
horse rapidly falls off — he becomes a dog-horse — and this disappear- 
ance of his fat coincides with the augmented exhalation of carbonic 
acid, which becomes remarkable at the period of eruptive and 
acute glanders. 
Another fact is, that the influence of excessive work may be 
counteracted, and even rendered harmless, by a large reparative 
alimentation. Demonstrative experience of this passed under our 
eyes, on a very extensive scale too, on the occasion of the con- 
struction of the fortifications of Paris. The horses worked hard in 
draught became glandered or not, according as they belonged to 
masters who could afford to (and did) keep them well or not. 
Most of the glandered horses were the property of unfortunate 
piece-workers ( tdcherons ) knowing little of the management of 
horses, and too parsimonious of their feed; while, on the other 
hand, the disease spared such as were well fed by wealthy con- 
tractors undertaking the work on their own account. 
XI. The labouring ox is not subject, on account of being worked 
up, to any disease having the least analogy with glanders. Not to 
notice his difference of organization, which is a principal considera- 
tion in this question, I contend that the difference of results from 
the same cause in the bullock and the horse is owing to the modes 
of using them, to the constant slowness of pace of the one, and the 
occasional and frequent rapidity of that of the other. This difference 
may cease to exist whenever the ox is forced into quick work, and 
especially should he be fat at the time. In such condition, under 
