MELANOSIS AND OSSIFICATION. 383 
through which the food lias passed, and thence insinuated itself 
into the near chamber of the nose, between the turbinated bones, 
whence it has become discharged through the near nostril. This 
will account for the annoyance and irritation set up on this side 
of the head, for the suppurated and even ulcerated condition of 
the Schneiderian membrane, for the suspicious discharges, &c. 
It was evident enough to veterinary examination that there was 
no “ glanders.” The very circumstance of alimentary matters 
making their occasional appearance with the nasal discharges was 
quite enough to lead to suspicions to the contrary. Even had the 
case been considered as and destroyed on account of glanders, it 
would have been by no means a singular one : an interesting case 
of the kind being related in “ Hippopathology,” vol. iii, p. 176. 
Ed. Yet. 
Second Contribution. 
Melanosis and Ossification of the Cells of the Vitreous 
Humour. 
History of the Case . — In the spring of 1848, I was visiting 
some diseased animals upon the farm occupied by the Messrs. G — , 
at Horsford, in this county, when my attention was directed to a 
white mare that had a tumour, about the size of a hen’s egg, situate 
on the superior and inner part of the left thigh, in the subcutaneous 
cellular tissue, close upon the posterior portion of the mamma, on 
the same side. It was at this period a loose, detached, and insen- 
sible body. 
The mare being in fine condition, and exceedingly fresh and vi- 
gorous for her age — sixteen years old ; bred upon the farm, and con- 
sidered by the proprietors the best doer and worker in their stable, 
they desired to have my opinion regarding the removal of this 
tumour. Upon inquiry, I learned that it was first observed when 
she was a filly by the side of her dam ; it was not larger, then, 
than a walnut, but it had increased in size somewhat of late. I re- 
plied that it might be removed, I believed ; but I thought, as it had 
existed for so many years without producing inconvenience, and 
taking her age also into consideration, I would rather wait and see 
whether it would continue to increase or not. 
She had hitherto been, apparently, quite free from disease of any 
kind, and continued to perform her duties for many months after 
this conversation to the satisfaction of the owners, although the 
tumour gradually, though slowly, increased in size, extending up- 
wards towards the mammae. 
I heard no more of her until early in the month of November 
