MELANOSIS AND OSSIFICATION. 
389 
poured ; for it could be scraped off, and the serous coats were still 
left smooth and entire.” 
Dr, Copeland informs us that this form of melanosis is not often 
met, with in man, but exists to a much greater extent in horses. 
4t,h. Liquiform melanosis more frequently occurs from the soft- 
ening of melanotic tumours ; it is sometimes seen in small quanti- 
ties in the cavities of the pleura and peritoneum. Liquiform me- 
lanosis is sometimes observed in the serous cysts formed in the 
capsules of the ova which have escaped from these ovaries, and in 
these organs. 
In The Veterinarian for 1839, we are informed by M. G. 
Andral, Professor to the Faculty of Medicine at Paris, that MM. 
Trousseau and Leblanc found, in a horse’s kidney, a fibrous cyst 
of the bulk of a fist, which contained about eight ounces of a black 
fluid. 
A fifth form of melanosis has been added by Dr. Noak, I believe, 
and very properly so, as far as the horse is concerned, which he 
calls melanosis ulcerosa] and which, he says, is more frequently 
met with in the horse than in man. My own case clearly establishes 
the existence of this form of the disease. 
It has been shewn that one or more of these forms may co-exist 
in the same animal, or any one may be present singly. The Tuberi 
form is the most common of all the varieties of melanosis: the dis- 
ease is never confined to one organ or tissue only, but is found to 
pervade a greater or less number, either successively or simultane- 
ously. It may be so extensive as to destroy the natural structure 
of the part, as occurred in the case of the white mare’s mammary 
gland. 
The bones are not often affected by this disorder; but MM. 
Trousseau and Leblanc, in The VETERINARIAN for 1839, mention 
the case of a white horse where the ischium was tinged black to a 
great depth, and was remarkably friable. 
In the Brain the disease is also rare, although in its healthy state 
it presents in certain parts a black colour ; and I have seen a case or 
two recorded of its occurring in this organ. It is hoped that I have 
shewn clearly the truthfulness of the foregoing classification of this 
disease, although but one case of each variety has been selected 
by way of illustrating the existence of these different forms. 
Being apprehensive that this communication has been extended 
already to an unreasonable length, I have purposely abstained from 
introducing others, though many such may be found in the pages 
of The Veterinarian. Such as may require further information 
on this subject I beg to refer them to its volumes, which abound 
in matter treating on this disease. 
Nature and Causes. — That melanosis depends upon a constitu- 
