30 
GLANDERS IN THE HUMAN BEING. 
me to give medicine, valuing neither time nor labour. In order 
to satisfy his mind, I ordered the blue draught (sulph. cupri) 
to be administered twice a-day. 
In the course of a week after this, the owner informed me that 
the horse had amended. Considering this rather a strange 
anomaly, I forthwith visited the patient, and satisfied myself that, 
instead of amending, he was quite the reverse, for blood was 
interwoven with the discharge ; the breathing was laborious and 
difficult, and, especially, it was accompanied by a very peculiar 
sound in the nasal passages. In a few weeks the proprietor told 
me that the horse had been sent to the knackers’ yard, and at 
the same time I heard that he and his man were similarly diseased. 
The smell and the discharge were of an identical character with 
those emitted by the horse ; and on examination my opinion fully 
coincided with his. From the resemblance of the characteristic 
symptoms in both a general description will suffice. The virus was 
conjectured to have entered the system, in one, through an abra- 
sion of the skin on the back of the hand, and in the other, through 
the medium of a sore on the low’er lip. The lapse of time prior to 
the appearance of the disease is not known. For a long time they 
continually smelled the nauseous effluvium that proceeds from 
glanderous matter ; there was an increased secretion of mucus 
from the nose, which was attributed to mild catarrh, until the cha- 
racter of the discharge, the blood intermingled with it, pain in 
the frontal sinuses and the cavities of the nose, and short and 
interrupted sleep, roused them to a state of anxiety, and made 
them dread the ultimate result. 
The pus with its gluey, slimy, glanderous appearance, 
satisfied me as to their real state. I could discern no distinct 
ulcers on the pituitary membrane ; but from the statements given 
by the patients, I should incline to decide that they existed in 
the remote parts of the nose. The throat, on pressure, was rather 
painful, and the lymphatic glands were enlarged. 
These patients having come so much under my own observa- 
tion, I shall give some account of the treatment of their respective 
cases by Dr. Elliotson. The servant was admitted into the 
North London Hospital, and the master attended by Dr. Elliot- 
son. 
By injecting a solution of creostote in water up the nostrils 
thrice a-day — by this simple means, and this alone — the servant 
was brought to a state of convalescence in ten days, and the master 
in a little longer time. If the local application of the creostote 
had proved insufficient, it would have been administered internally. 
The strength of the injection was changed according to the stimu- 
lating effect produced. At first the cases admitted of two mi- 
