CONTAGIOUS CHARACTER OF STRANGLES. 585 
also whether the virus belonging to these two affections would 
produce different lesions in the two nasal cavities. 
Nothing; remarkable occurred until the fourth dav after the 
inoculation, when a slight flux from the right nostril was ob- 
served. 
On the 5th day it had considerably increased. 
6th day . — A discharge appeared from the left nostril also. 
The ala of the right nostril was tumefied, and also the lymphatic 
glands beneath the jaw on the same side. 
7th day . — The discharge was very abundant from both 
nostrils. They were much swelled, and the swelling extended 
up to the forehead. The animal was very much out of spirits. 
8th day . — The same discharge and swelling, but the animal 
was becoming rapidly weak ; the breathing was difficult, and 
the pulse small and quick. The animal died before night. 
The pituitary membrane was, generally speaking, highly in- 
flamed, but especially on the right side, and there was pus 
within the turbinated bones and in the sinuses. The left lobe 
exhibited tubercles of long standing ; the right one was con- 
gested, and easily lacerated. 
Exp. II. — At the commencement of April we deposited, on 
six successive mornings, with the feathered part of a quill, on 
the nasal membrane of a horse six years old, some of the matter 
from the nostril of a colt that had strangles. The horse was 
also left twenty days in the place which had been occupied by 
the colt. Not the slightest effect was produced. 
Exp. III. — The same kind of matter was introduced into the 
nostril of a young ass, and he was turned into the stable in 
which the horse with strangles had been. No effect was pro- 
duced. 
Exp. IV. — The same kind of matter was, during ten days, 
introduced into the nose of a young ass, only four months old. 
On the 7th day after the commencement of the experiment, 
the lymphatic glands between the jaws began to swell, and the 
enlargement increased daily. 
12 th day . — A discharge from the nostrils now appeared, and 
the swelling continued to increase, but the animal did not exhibit 
any other symptom of illness. 
1 6th . — The abscess now seemed to be ripe. It was punc- 
tured, and a great quantity of pus of good character proceeded 
from it. 
20 th day . — The flux from the nose had ceased, and the 
wound between the jaws was healed. 
Exp. V. — The same experiment was made on a mule, aged 
sixteen or eighteen years, but without effect. 
