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REVIEW — COGSWELL ON IODINE. 
night he passed two black, scanty, semi-fluid stools. The fol- 
lowing day he maintained the same constant posture on the side, 
rejecting nourishment, and complaining loudly if handled. On 
the third day, the animal lay stretched completely on the side; 
the eyes and mouth closed, and the jaws moist with saliva, under 
which circumstances death took place late in the evening. 
Inspection . — The body was rigid. Over the artificial cavity 
for the poison the hair and cuticle easily came away ; and the 
walls were lined with a layer of thin, soft matter, resembling in 
appearance cream tinged with blood ; the right cavities of the 
heart were filled with dark fluid blood ; the left ventricle con- 
tained a small dark coagulum ; the stomach was flaccid, but 
contracted slightly on exposure to cold water ; its inner mem- 
brane presented moderate diffuse redness.” “ Mr. Cogswell de- 
tected combined iodine in the blood from the heart, in the brain 
and spinal cord, the liver, spleen, stomach, muscles, tongue, 
and the bones, freed from their appendages; likewise in the con- 
tents of the bladder.” 
“ Half a drachm of hydriodate of potash, dissolved in half an 
ounce of water, slowly injected into the jugular vein of a strong 
dog, produced a feeble cry and general spasmodic contraction, 
with evacuation of the urine and faeces : in a few seconds the ani- 
mal fell powerless, with the saliva flowing, the tongue hanging 
out, and its fibres oscillating. When opened ten minutes after- 
wards, the body exhibited the brain and spinal cord congested, 
and partially-coagulated blood filling the right cavities of the 
heart.” 
“ In a similar experiment with four grains on a smaller dog, 
death took place in about a minute.” 
“ A quantity of the hydriodate in solution produced vomiting. 
Devengie then introduced a solution of two drachms, and tied 
the oesophagus. Immediate depression followed, and death on 
the third day.” 
“ Three drachms in solution destroyed a larger dog (with the 
gullet tied) in about the same time. The body remained flaccid 
after death.” 
A drachm of the hydriodate, dissolved in two drachms of water, 
were introduced into the stomach of a strong male rabbit. “ The 
animal instantly became depressed, and refused his food and 
“ on the third morning it was found dead.” 
“ Enough has been said to shew that, so far as it has been 
tried, the hydriodate of potash exercises a powerfully irritant 
action on the digestive canal of the lower animals, and that, at 
least, some individuals of our own species are liable to be affected 
in a similar manner.” 
