128 
Vaccination. 
[March, 
with the practice which may be distinguished, though not 
scientifically definable, — the disease a la Jenner, a la Ceely, 
and a la Cameron, all supposed to be prophylactic of small- 
pox. According to Jenner it was the disease of cowpox, and 
that not the eruption arising as an outward manifestation of 
bad health in the cow, but the effedt of transmission from 
the diseased horse, by the accident of dirty grooms adding 
as milkmaids. He describes the effedt of inoculating this 
disease upon the healthy human frame : — “Absorption takes 
place, and tumours appear in each axilla. The system be- 
comes affedted, the pulse is quickened ; shiverings succeeded 
by heat, general lassitude, and pains about the loins and 
limbs, with vomiting, come on. The head is painful, and 
the patient is now and then even affeCted with delirium. 
These symptoms, varying in their degree of violence, gene- 
rally continue from one day to three or four, leaving ulcerated 
sores about the hands, which, from the sensibility of the 
parts, are very troublesome, and commonly heal slowly, fre- 
quently, becoming phagedenic, like those from which they 
sprang.” A little further on in the same treatise he re- 
marks “ But what renders the cowpox virus so extremely 
singular is, that the person who has been thus affeCted is 
for ever after perfectly secure from the infection of small- 
pox. Vaccination of this kind is now seldom met with ; 
but a case, a few years ago, fell under our observation in 
which the prediction was certainly fulfilled, for the infant 
succumbed in a few days, and the rarity of the occurrence 
was attested by the medical attendant certifying the death 
as fiom measles. When the gentle and reverend father 
meekly suggested that the measles were of an unusual kind, 
the reply was “ Yes, they were suppressed, you see.” And 
so was the truth at the same time, by honest ignorance. 
The disease a la Ceely originated about fifty years after 
the disease a la Jenner. The more frequent occurrence of 
smallpox after operations for cowpox gave rise to the idea 
that the virus was enfeebled, attenuated, or diluted beyond 
the point of usefulness, and that it required to be renewed 
or somehow strengthened. This led to the development by 
Mr. Ceely, of Aylesbury, of the notion that the cowpox and 
smallpox were essentially identical, by inoculating matter 
taken from smallpox patients on cows, and subsequently 
inoculating the human frame with the product. The result 
was the appearance of normal vaccine vesicles. This per- 
formance was lauded in the House of Commons, by Mr. 
Lowe, as the most wonderful improvement in the practice 
of vaccination, and was by some supposed to supply a more 
