ON GLANDERS. 497 
concurred ; but Mr. Balguy expressed his wish that the case 
should go to the jury. 
The learned Judge having charged the jury, they, after some 
slight deliberation, returned a verdict for the defendant on the 
issue of unsoundness, and for the plaintiff on the other issues. 
ON GLANDERS. 
INTRODUCTION OF PURULENT MATTER, TAKEN FROM A 
HORSE NOT AFFECTED WITH GLANDERS, INTO THE VEINS 
OF A MARE DEVELOPMENT OF ACUTE GLANDERS — INO- 
CULATION WITH THE GLANDEROUS MATTER THUS PRO- 
DUCED — THE PRODUCTION OF GLANDERS. 
By Messrs. Renault and H. Bouley. 
A mare, nine years old, and of excellent constitution, was 
brought to the Veterinary College at Alfort, on account of lame- 
ness in the right hind-leg. It was fracture of the os innomina- 
tum; and the owner, to avoid the chances of long surgical treat- 
ment, had abandoned her to the school. She had been kept a 
month in the hospital, and a variety of clinical experiments had 
been tried on her. The lameness not decreasing, we attempted 
the experiment about to be described. 
She had every symptom of health except her lameness — no flux 
from the nose, or enlargement under the jaws. The respiration 
perfectly normal, the pulse regular, and the mucous membranes 
presenting their natural colour. 
On the 22d of April in this year, we took some healthy pus 
from the tail of a German horse that had been nicked, and from 
a seton in a mare. The quantity collected consisted of about two 
drachms, which was mixed with a little distilled water, and 
passed through a cloth filter. After being thus filtered, it had 
the appearance of a yellow opaque and perfectly liquid emulsion. 
We then opened the jugular vein with a large fleam, and, by the 
assistance of a funnel introduced with precaution into the orifice, 
we caused it to mingle with the blood. 
Immediately afterwards her respiration was disturbed; the 
movements of the flanks were precipitate, and violent; her sides 
rose and fell convulsively, and the nostrils were much dilated. 
The pituitary and conjunctival membranes became red ; the pulse 
beat violently, and the movements of the heart were tumultuous. 
Five minutes afterwards she twice voided a considerable quantity 
of faecal matter. 
3 T 
VOL. XIV. 
