ON GLANDERS. 
499 
and appear as if they were distended by fluid; around is a deep 
red areola. The discharge now dries on the nostrils, and adheres 
there. The breath has a faint sickly smell. A farcy eruption is 
observed around the nose, and eyes, and cheeks, and neck, and 
on the outside and inside of the thighs: every symptom is now 
aggravated. 
May 1st . — The ulcerations in the nasal cavities are enlarged. 
The mucous membrane of the nose presents large black petechial 
spots. The aim of the nose are infiltrated, and the respiration 
through the nose is attended by a whistling sound. Large farcy 
cords now run like ridges along the cheeks and the ganglions of 
the lower jaw, which are very much enlarged, and the buttons 
and the cords are multiplied over the whole surface of the animal. 
The oedema of the chest increases, and extends far along the 
chest. The hind limbs are become so large, that the animal 
finds considerable difficulty in walking. The respirations are 
precipitate, the pulse is scarcely perceptible, and the contractions 
of the heart are tumultuous. Towards the evening the patient 
became so weak that she was no longer able to stand. She fell, 
and, after some convulsive motions, died. 
Examination , ten hours after death : — 
The nasal cavities .—The mucous membrane which lines the 
interior of the nasal cavities is the seat, throughout its whole 
extent, of a livid red injection. This colour is deepened by the 
sanguineous engorgement of the large subjacent venous sinuses. 
In the superior part of the nasal cavities the tissue is completely 
black. On the surface of the pituitary membrane, as well upon 
the cornets as the septum, are spots of a yellow white, irregularly 
formed, and of various dimensions — here isolated like small tu- 
bercles, and there deposited in lines, and in some places as large 
as marbles. Scattered about were ulcerations, having projecting 
borders, white, infiltrated, and surrounded by a livid red areola. 
These ulcerations were in some places so united together as to 
form one vast wound. The changes had more perfectly taken 
place on the left side than on the right. The frontal sinuses 
were filled with citrine-coloured serosity. The membrane which 
lined them presented one vivid vascular injection. 
The lungs . — The left was more affected than the right. Its 
surface presented a great number of elevations, which projected 
under the pleural envelope, and gave to the hand that explored 
them the sensation of large tubercles buried in the substance of 
the organ. These granulations, being cut into, present very dif- 
ferent appearances. Some of them seemed to be formed of a very 
circumscribed infiltration of black blood into the pulmonary tissue. 
Others exhibited a red areola at their circumference, and their 
