GLANDEKS IN THE HUMAN SUBJECT. 5*25 
charge of sanious fluid from the left ear, but none from the 
nostril. 
On the 29th a farther exacerbation of symptoms took place. 
The left elbow joint was swollen and painful — the pustules in- 
creased in number and size, and were intermixed with gangrenous 
bullte ; and, along the internal and anterior parts of the thighs, in 
the situation of the absorbents, pale rose-coloured swellings began 
to appear. His breath was foetid, and the odour from his whole 
body was almost insupportable. He had no discharge from the 
nostrils, but on examining the nose. Dr. Hutton observed a small 
ulcer on the left side of the septum nariuin. The man died 
during the course of the night. 
On post-mortem examination, a great number of small circum- 
scribed abscesses or purulent depots were found in the extremities 
— as many as thirty were on the left arm. There were two or 
three of the same kind in the pectoralis major, and several of 
the same description in the recti of both thighs, all circumscribed 
and embedded in the muscular tissue. In the left lung there was 
a small depot of pus surrounded by a dark livid border and another 
of the same kind was discovered in the right lung. On the 
posterior surface of the heart there were dark-coloured spots, and 
the blood was remarkably fluid in all the vessels. There was a 
deposition of pus under the mucous membrane of the larynx, and 
also on the posterior surface of the epiglottis. The left half of the 
face was in a semi-^ano-renous state. 
On the 27th of August, the day after Kelly’s admission, the 
experiment was again repeated on another ass with matter taken 
from the vesicles and pustules on his body. The lymph was 
inserted into the left nostril of the animal, the pus into the oppo- 
site one, and it was also inserted into the ear. On the following 
evening the ass appeared unwell, and, on the next day had an 
enlargement of one of the glands of the jaw on the left side, with 
increased heat and tenderness, accompanied by feverish symp- 
toms. The left ala nasi was swelled, and the line of absorbents 
from this to the glands on the side of the jaw could be distinctly 
traced. On the next day there was a profuse watery discharge 
from both nostrils, particularly the left ; and on the following day 
— the fifth day after inoculation — the discharge was purulent. 
Soon afterwards the animal was killed with nux vomica, it having 
been previously ascertained by Mr. Ferguson, V.S., that it was 
really glandered. 
On examination, a cluster of pustules having a tubercular aspect 
were found in the left nostril : in the ricrht there were circular 
patches of ulceration. Similar ulcers were found in the interior 
of the stomach, and there was a cluster of pustules in the anterior 
VOL. XIV. 3 z 
