526 
GLANDERS IN THE HUMAN SUBJECT. 
lobe of one lung. There was no morbid appearance in the larynx 
or trachea. 
Dr. Hutton exhibited several drawings to shew the condition 
of the various parts, particularly the nostrils, stomach, and lungs. 
The next case, to which he would merely allude, as it was 
about to be published by Dr. M’Donnel, who had charge of it, 
had occurred a short time ago at the Richmond Hospital. The 
patient was admitted for an accident, from which he recovered: 
but before he left the hospital he was seized with an affection of 
the joints, followed by an eruption of pustules along the side of 
the nose, which were recognized as being connected with glanders. 
Mr. Smith procured some of the matter, and inoculated an ass, 
which in the course of four or five days became sick, and was 
subsequently attacked with glanders. The same phenomena as 
observed in the last case of inoculation were present. The carti- 
lages of the joints were also found to be ulcerated. 
Dr. Hutton exhibited some drawings to shew the condition of 
the parts. He also produced one of a case that had occurred 
some years ago at the Richmond Hospital, under the care of the 
late Dr. M’Dowell, before the disease was sufficiently known. 
The drawing had been made by Mr. Conolly, and Dr. Hutton 
observed, that he had represented the features of the disease with 
great accuracy, and depicted most faithfully the white areola 
which encircles the vesicles. 
Since that period the areola has been invariably found to be 
present in every case, and is regarded as one of the pathognomonic 
features of the disease. This has been also noticed by Dr. Hut- 
ton, Mr. Adams, and other observers, and forms one of the marks 
by which the disease is distinguished from phlebitis. 
Dr. Hutton then said that he should next proceed to read the 
notes of a case that had recently come under his observation. 
«/ 
The patient, T. Butler, a boy about five years of age, was 
admitted into the Richmond Hospital on the 18th of December, 
1840. It was stated that he had been always a fine healthy 
child up to the period of his illness. He complained at first of 
sickness, and pain in his bowels, and, on the following day, had 
pains in his knees. About three days afterwards the left side of 
the face and eyelid became swollen, and the usual symptoms of 
irritative fever set in, accompanied by thirst, restlessness, quick 
pulse, and scanty urine. 
On the 5th of December the fever was increased, and the 
other side of the face was involved in swelling. On the 7th, a 
number of pimples with white tops appeared on the inflamed 
surface. On the 13th, the date of his admission, his face was 
greatly swelled and inflamed, and presented a number of pustules 
