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HISTORICAL RESEARCH ON THE EPIZOOTIC. 
At the third period, a crust has been formed on the pustules, 
which soon comes off*. This happens about the seventh day, or 
later, when the case has been severe. At the same time as the 
eruption begins to disappear, tumours appear at the feet, the 
fever abates, and the appetite returns by degrees. 
The epizootic that prevailed in Moravia in 1764, attacked neat 
cattle, sheep, goats, and swine. The two latter suffered most, 
and the disease was more fatal to them. 
The milk of the affected animals was not so sweet as in health, 
and was observed to curdle as soon as it was brought near the 
fire. Those who made use of it felt a sensation of heat and con- 
striction about the throat, and soon contracted the disease. 
The same epizootic prevailed in 1763 and 1764 in Auvergne, 
and in the Perigord ; and also in the neighbourhood of Paris. It 
mostly attacked neat cattle and horses. It was observed 
principally in the capital and near Alfort. It continued in 1810 
in the department cf Calvados, chiefly attacking neat cattle and 
sheep: it also prevailed about the same time in Italy, without 
any variation in its characters, running its course from ten to 
twenty days, without any great loss of life. In the two species 
of ruminants which it attacked there appeared ulcers on the in- 
terdigital portions of the feet, and which caused great pain and 
lameness. 
In 1810, and in the neighbourhood of Lyons, besides cattle, 
goats, and sheep, it also attacked the monodactyle. It was ob- 
served at the same time in different parts of Switzerland. The 
epizootic which manifested itself in 1764 attacked nearly all do- 
mesticated animals, and renewed itself in 1819 in the department 
of Oise ; presenting, besides the ordinary characters of the epi- 
zootic, some remarkable peculiarities ; viz. great swelling of dif- 
ferent parts of the head at the time that the pustules made their 
appearance. The tongue, in particular, was so much swollen 
that it protruded three or four inches out of the mouth. The sub- 
lingual ganglia became swelled and tumefied, sometimes to the 
size of a large egg, and which often terminated in abscesses ; but 
the disease was mild in some cases. 
Pouchet and Potolle, who have closely followed this disease, 
do not mention the lesion of the feet, which, probably, did not 
exist in this instance. 
The treatment recommended by Hurtrel D’Arboval consists, 
first of all, in a well-regulated diet ; a clean and airy lodgment, 
in which the temperature is to be well regulated, particularly so 
as not to fall too low. To the herbivorous animals he recom- 
mends warms drinks acidulated with nitre ; and, when the appe- 
tite is not much impaired, green food of the best quality should 
