404 A CASE OF GLANDERS IN THE HUMAN SUBJECT. 
Case. — Mr. Pink, set. 52, carrier, and proprietor of a London 
waggon-office, was wounded in the thick part of the thumb of 
the left hand by a nail, on the 17th of March, 1841. Part of 
the nail was so buried in the flesh that the surgeon was obliged 
to cut down upon it for the purpose of removal. The wound 
progressed satisfactorily, and, on the 30th of March was nearly 
healed. 
On the 3d of April Mr. Pink complained of being unwell, 
with pains in the limbs, head-ach, and feverish heat." On the 
second day following he sent for Mr Porter, his ordinary medical 
attendant, who found him labouring under severe febrile symptoms, 
with considerable pain in the left wrist, arm, and shoulder, and 
an inflammatory blush, with slight swelling on the back of the 
left hand and wrist. Two days following he complained of in- 
tense pain over the inferior angle of the scapula ; the part ap- 
peared swollen, red, and hard to the touch. A similar swelling 
took place on the outside of the left leg, attended with the like 
pain, which eventually formed matter, and on being opened on 
the 16th, gave exit to a thin purulent bloody sanies. The fol- 
lowing day his symptoms were worse. He complained of intense 
pain in the left knee-joint; indeed, it was so exquisitely painful 
that he could not bear its being touched ; pain over the frontal 
region : left upper eyelid swollen, of a dusky erysipelatous hue : 
discharge of a thin bloody sanies from both nostrils ; dry, brown, 
furred tongue ; low muttering delirium, pulse quick, compressible, 
and weak, but regular. About the eighth day of the disease 
several small subcutaneous tumours were observed by the touch 
only, the integuments covering them not being elevated or dis- 
coloured ; these were moveable, hard, oblong, and isolated. 
The febrile symptoms became more and more severe ; and on 
April the 20th, I was called in consultation. The fever was at- 
tended with the usual typhoid symptoms, &c. . He complained 
of pain on being moved, particularly in the left arm and shoul- 
der ; the eyelids were inflamed, and partially closed by the dusky 
tumefaction of the palpebrse ; several small tumours were disco- 
verable under the cutis, varying in size from that of a split pea 
to that of a split kidney-bean ; similar tumours were observed on 
the forehead, but these were tubercular, being elevated above 
the surrounding skin ; considerable discharge of brown sanies 
from his nostrils. The typhoid symptoms were more severe on 
the following day ; and in addition to the above symptoms were 
discovered an eruption of pale vesicles, resembling that of vari- 
cella, over various parts of the body, some containing pellucid 
lymph, others opaque puriform fluid, and others were desiccated. 
These symptoms so much resembling glanders occurring in 
