266 TRANSFUSION OF BLOOD IN THE HORSE. 
trough containing the hot water to maintain its temperature, 
and the other curved tube into the descending portion of the 
vein in the patient. As soon as the current from the healthy 
horse had completely expelled all atmospheric air, the in- 
strument being thus arranged, the blood flowed freely from 
the vein of one horse into that of the other in an unbroken 
current. The average quantity of blood transfused in each 
of these cases was about three quarts. I observed no 
particular symptoms to follow from the transfusion, until 
two quarts or more had passed from the healthy to the 
diseased subject ; but as soon as about that quantity had 
flowed, there appeared to be produced an amount of stimu- 
lation indicated by an increased action of the heart ; at the 
same time the pupils began to dilate, and the countenance 
evinced an anxious expression. My former experiments led 
me to watch with great care the progressive dilatation of the 
pupil, and I deemed it expedient in each case, when this 
symptom was well developed, to compress the tube so as to 
diminish the current and allow the transfusion to proceed 
more gradually and slowty. Occasionally I almost com- 
pletely interrupted the current until the subsidence of this 
symptom ; and I found that, when about three quarts had 
been transfused, any additional quantity was followed by 
unpleasant symptoms, which indicated the necessity of 
stopping the operation. On removing the tube and closing 
the vein, all symptoms of irritation gradually subsided ; and 
the pulse, from being rapid and irritable, became slower, 
stronger, and fuller, gradually approaching the healthy 
standard. 
In each of these four cases the reaction was steady and 
progressive. The natural warmth of the extremities was 
gradually restored ; and in the course of ten or twelve 
hours the patient presented other equally unmistakable 
sj'mptoms of amendment, such as returning appetite, more 
quiet and steady respiration, cheerfulness of countenance, 
and a willingness to move about : from this point there was 
a gradual improvement, and in a short time they were pro- 
nounced cured. 
I have been induced to submit these few remarks, much 
less with a view to record any little success I may have 
had in performing the operation myself than with a hope 
that others, far more capable, will take up the matter and 
test it thoroughly; for whatever obstacles and objections 
there may be to its performance in the human subject, there 
are none to prevent its becoming a most valuable agent in 
veterinary science. — j Dublin Quarterly Journal of Medical 
Science. 
