44 
ON THE PRESENCE AND EFFECT 
of a dog, and very carefully confined there : he was thirsty and 
feverish for fifty-five hours after the operation, when he was killed. 
An ounce of fluid, almost entirely serum, was found in the 
pleura, and some fibrinous exudation on the membrane. 
Blood from the heart, as well as from the vena cava, was exa- 
mined, and found to contain several pus-globules. 
Exp. 5. — Four ounces and five drachms of pus were injected into 
the peritoneum of a dog, and the wound carefully closed : he died 
thirty-seven hours after the injury. 
There were only nine drachms of a sero-sanguinolent fluid found 
in the peritoneum, and a considerable quantity of coagulated lymph 
on the membrane. 
Pus was detected in the blood. 
Exp. 6. — Half a drachm of pus, mixed with half an ounce of 
water, was gradually injected into the crural vein of a dog. 
Some fever followed, and he refused solid food for two days, 
but recovered at the end of a week. 
The same quantity of pus was soon afterwards injected into the 
other crural vein, when similar symptoms were produced, and he 
perfectly recovered in a few days. 
Exp. 7. — Six drachms of pus having been injected into the 
crural vein of another dog, he was not much affected at first, but 
in a few hours became very weak, was stupid, thirsty, and refused 
his food. After thirty hours he took but little notice of surrounding 
objects, his respiration was hurried, and he died thirty-six hours 
after the operation. In the blood of the inferior cava some pus- 
globules were readily detected. 
Case I. — A girl died of confluent small-pox on the ninth day of 
the disease. There was great swelling of the integuments. 
In the blood of the right ventricle numerous pus-globules were 
found. 
Case II. — A woman had confluent small- pox, uncomplicated 
with erysipelas or inflammation of the viscera. 
On the eighth day of the disease, some blood was drawn from a 
vein in the arm : several pus-globules were found in this blood. 
Case III. — A male child, set. 15 months, died on the ninth day, 
of small-pox. Only a few pustules appeared, and these were im- 
perfectly developed : there was considerable swelling in the face, 
slighter in other parts. 
At the post-mortem examination, it was observed that a small 
quantity of a white opaque fluid might be squeezed from the cut 
surfaces of the lymphatic glands of the neck and groin : this fluid 
had the microscopic and chemical characters of pus. 
In some blood obtained from the right ventricle and from the in- 
ferior cava vein, pus was detected. 
