192 COMPTE RENDU OF THE SCHOOL AT LYONS, 
yellow-coloured infiltration in the subjacent cellular layers. This 
infiltration extended to the inside of the thighs, and under the 
belly. The mammillary glands were only in the first stage of 
scirrhous degeneracy. The abdominal and thoracic viscera were 
healthy. 
This fact establishes the occasional existence of a cancerous 
affection, remaining for a long time altogether local ; bounded by 
the parietes of the vagina, and only extending to the mammae in 
its last stage. 
Although these are cases in which the patients have sunk under 
the influence of the disease, and our medical treatment has been 
insufficient, we have not feared to publish them, being convinced 
that the record of a failure often leads to the most unexpected 
and valuable discoveries. 
We have conducted certain experiments at the instigation of M. 
Bonnet, surgeon-in-chief at the Hotel Dieu at Lyons, with a view 
to ascertain whether the haemorrhages which occur in the first days 
after amputation, and which are so often followed by the death of 
the patient, derive their danger from the simple loss of blood, or 
from the moral impression which the amputation ordinarily makes. 
He amputated the leg of two dogs at the same time, leaving the 
blood to flow from the wound of one of them to the amount of six 
ounces, which is the maximum in bleeding this animal* : from the 
other, one or two ounces alone were subtracted during the opera- 
tion, and two venous bleedings of an ounce each were made, with 
an interval of three hours between them, and on the following day 
three other bleedings, to the same extent, and with the same in- 
terval of time. 
In the first dog the wound healed rapidly by the first intention, 
as is usual in the dog ; but the second was very much dispirited 
during the two or three first days, and there was a cold skin and 
small pulse. These symptoms, however, gradually disappeared, 
and the wound healed in a little longer time than in the first case. 
The same experiment was repeated on two other days, and with 
the same results. 
Inflammation of the viscera of the chest were of frequent 
occurrence in the spring and summer of this year. Our treat- 
ment has had a very satisfactory result. The veterinary sur- 
geon has, within the few last years, made himself far better ac- 
quainted than he used to be with the existence and character of 
diseases of the chest. We refer to the adoption of percussion 
* I have often taken ten and twelve ounces from a dog of middle size, and 
have abstracted, and with good effect, sixteen and eighteen ounces from a 
Newfoundland dog. In cases of acute inflammation, six ounces would very 
rarely have satisfied me. — Y. 
