USE OF CREOSTOTE IN THE HUMAN SUBJECT. 225 
Schneiderian membrane, and which was extending upwards. He 
ordered the solution already prescribed to be injected up the nos- 
tril, and he ordered small doses of calomel. Carrot poultices 
were applied occasionally, which gave temporary relief. Sarsa- 
parilla was also prescribed. 
A second physician had been called in, but, the case going on 
unfavourably, and I being dissatisfied with the treatment, I wrote 
to you and to Sir Astley Cooper*. 
On the night on which my letters were despatched, the disease 
began to assume a most alarming appearance, and I urged his 
medical attendants to have recourse to the creostote, and, indeed, 
which I had before pressed upon them. They consented, and 
prescribed an ointment in the proportion of ^i of the creostote to 
3vii of lard. The slightest application of this produced the most 
agonizing pain, and, of course, it was immediately discontinued, 
and the creostote was condemned. I affirmed that no fair trial had 
been given to it ; and, as they now considered the case of my son 
a hopeless one, I respectfully told them that I should pursue my 
own course. 
The disease had now assumed the most fearful character : there 
was profuse nasal discharge, accompanied by the most offensive 
smell, and ulceration extending into and seemingly occupying the 
whole of the nasal cavities. There was great prostration of strength 
— cold perspirations — pulse 112 — laborious breathing — and every 
appearance of approaching death. 
I added two minims of the creostote to an ounce of water, and 
injected the mixture up the nose as high and as universally as I 
could, and this I repeated three times in the day. I pledge you my 
honour, that, after the third injection, a change almost magical took 
place. The discharge in a great measure ceased, and, two days 
afterwards, the ulcers began to assume a healthy appearance, and 
they have rapidly improved ever since. Before your kind letter 
arrived, I had considered him out of danger ; and most gratified 
was I to find that I had been using an injection of preciselv the 
same strength as that which Dr. Elliotson recommended. 
The ulcers have now lost all their chancerous character, and are 
assuming a healthy granulating appearance. His diet was nutri- 
tious, but no solid food allowed ; and in the course of every day 
he drinks a tumbler full of good ale. Yesterday he rode out for 
an hour. 
From the extraordinary effect of the creostote in my son’s case. 
I am determined to try it on the next glandered horse that comes 
under my care ; and I shall consider it a peremptory duty which I 
* To the letter which I received was appended one from Dr. Conolly, of 
Waterford, highly creditable to his candour and his talent. 
