548 
ON INOCULATION WITH THE 
cite two cases to the contrary, in the whole of the southern pro- 
vinces, and yet they are suspicious.” 
Massie, a celebrated physician, and who lived in the very centre 
of a district that was depopulated by the disease, says, in a memoir 
addressed to Yicq. d’Asyr, that “ experience has taught him that 
an ox cured of the epizootic disease is of inestimable price, because 
he can brave with impunity every danger to which he may be 
afterwards exposed.” 
In 1770, after the system of inoculation had been established in 
Germany by Berger and CEder, eleven beasts that had been thus 
inoculated were sent into Zealand, where the typhoid epizootic still 
raged. They were dispersed among the herds that were daily 
thinned by the malady — they were placed in cow-houses in which 
were animals either dying or dead — they were submitted to every 
possible trial, without one of them being infected. 
Claus Detlof, after having inoculated eight calves, and commu- 
nicated to them the disease, inoculated them again, no less than 
three times, but without success. He placed them in stables in- 
fectious in the highest degree, but they did not contract the disease. 
Bulow inoculated nine cattle. They all of them contracted the 
disease — five under a severe form, and four lightly. They were 
all inoculated a second time, but without any result. They were 
then sent into a locality at that time free from disease ; but the 
malady soon reached and destroyed the greater part of the cattle. 
These animals alone resisted the contagion by which they were sur- 
rounded. 
Claus Detlof sent thirty beasts that had recovered from the ino- 
culated disease into a certain district in which no fewer than seven- 
ty-three cattle perished in the space of a few days. They were 
kept in the same cow-houses ; they were fed in the same manner as 
the others, but not one of them became infected. 
Camper sums up all these cases by saying, that cattle recovered 
from the inoculated disease perfectly resisted a second contagion, 
whether natural or artificial. 
In 1815, Messrs. Girard and Dupuy, after having transmitted 
the prevailing typhus to three cows by means of inoculation, re- 
inoculated them, and exposed them to infection in every possible 
way, but neither of them contracted the disease a second time. 
These observations and facts are very numerous, and they are 
recorded by persons deserving of all confidence, and thus they prove 
that the animals that have had typhus, either in the natural way or 
by means of inoculation, are preserved from all after-infection. 
Negative Facets . — Camper relates that six beasts that had been 
inoculated by Grashuis, and perfectly cured, were attacked by an 
epizootic which afterwards prevailed, and four of them died. 
