308 Sir James Earle's Account of a Calculus 
increased effect, in proportion as he became less capable of 
supporting them. Toward the eighth day from the operation, 
he was visibly growing weaker, his pulse smaller and quicker, 
his little inclination for food became less, and he was with 
difficulty prevailed on to take any ; some cordial medicines, 
however, in some degree revived him ; but on the ninth day 
he grew more impatient, feverish, and restless, and on the 
twenty-first of August, ten days after the operation, he de- 
sired not to be teased to take any thing more ; when, covering 
himself completely with the bed-clothes, he quietly resigned 
a most singularly miserable existence. 
Examination after Death. 
On opening the abdomen, the bladder was found much dis- 
eased and thickened, firmly embracing a stone of extraordi- 
nary magnitude, and appearing to be completely filled with it. 
On dividing the bladder from the os pubis backwards to the 
rectum, the stony mass was uncovered, which I attempted to 
take away with the largest forceps ; blit it was impossible. It 
was then raised by getting the hand under it, with consider- 
able difficulty, as the cohesion between the bladder and the 
stone was very strong, though there did not appear to be any 
diseased or distinct adhesions. When taken out, the form of 
the stone appeared to have been moulded by the bladder ; the 
lower part, having been confined by the bony pelvis, took the 
impression of that cavity, and was smaller than the upper part, 
which having been unrestricted in its growth, except by the 
soft parts, was larger, and projected so as to lie on the os 
pubis. 
A large excavation had been made in the lower part, which 
