gio Sir James Earle’s Account of a Calculus 
on till the whole cavity was nearly choked up. From the 
appearances on the examination, it is more than probable that 
the mouths of the ureters would have been soon completely 
closed, when a total, and consequently fatal suppression of 
urine must have taken place. 
The disease probably originated when the patient was 
obliged to continue such a length of time on his back, in which 
position the surface of the water only may be supposed to have 
been, as it were, decanted, and the bladder, seldom, if ever, 
completely emptied ; thus in a constitution, perhaps naturally 
inclined to form concretions, the earthy particles subsided, 
and by attraction soon began to lay the rudiments of a stone, 
which was not felt above the brim of the pelvis till many years 
after, but from that time the gradual increase of it was per- 
ceptible to the patient, and his medical friends : from this cir- 
cumstance, as well as the shape of it, the stone evidently 
appears to have commenced within the pelvis, and in the 
lowest part of the bladder. 
The texture of it appeared different from the generality of 
calculi, and to contain more animal matter. In a short time it 
became highly putrid and offensive : after macerating a few 
hours in fresh water, the saline particles in its composition 
began to separate, large flakes separated from its surface, 
and I was convinced, that if the maceration had been conti- 
nued, the whole of the outer part would have crumbled away; 
it was therefore suffered to dry, and the putrid effluvia gra- 
dually wept off. As a proof that animal matter abounded, the 
calculus not having been protected from the flies, maggots 
were produced in it at the end of a fortnight, which were 
destroyed by washing it with spirits. 
