228 
Mr. W. Brande on the Differences 
3. Calculi, containing oxalate of lime ; commonly called 
mulberry calculi. 
These are distinguished by the difficulty with which they 
dissolve in dilute acids, by their hardness, and by leaving 
pure lime, when exposed to the action of the blowpipe 
In the examination of these calculi, I was struck with the 
small number of those strictly belonging to the first division, 
having been led, from the account of Fourcroy and Vau- 
quelin,* and the experiments of Dr. Pearson,^ to believe 
that calculi, composed of pure uric acid, were by no mean 
un frequent. 
The greater number of the calculi examined by the former 
chemists, are stated to be completely soluble in the fixed al- 
caline leys ; and of three hundred examined by Dr. Pearson, 
a large proportion is said to consist of uric add. 
The following is a statement of the composition of the dif- 
ferent calculi found in the bladder which I have examined. 
16 were composed of uric acid. 
45 — — uric acid with a small relative pro- 
portion of the phosphates. 
66 . — — — __ the phosphates, with a relatively small 
proportion of uric acid. 
12 ______ of the phosphates entirely. 
5 — — of uric acid, with the phosphates and 
nuclei of oxalate of lime. 
6 . — — — — chiefly of oxalate of lime. 
350 
* Annales de Chemie., xxxii. 21S. 
f Philos. Trans. 1798. p. 37. 
