Mr. Home’s Observations on 
24 6 
number prevented the pressure from being, great upon any 
one part of the intestine immediately behind the bladder, and 
their motion on one another rendered their external surface 
smooth, and probably prevented their rapid increase. The 
other patient was under a course of Perry’s lixivium ; and 
when the symptoms went away, he published the case in 
proof of the efficacy of that medicine in dissolving the stone. 
I examined the bladder after death, and found fourteen 
calculi ; the largest of the size of a nutmeg, the others 
smaller. There was the same enlargement of the posterior 
lobe of the prostate gland, and the calculi were exactly 
under the same circumstances as in the former case. 
In several cases, in which I have examined the body after 
death, calculi have been found inclosed in cysts, formed be- 
tween the fasciculi of the muscular coat of the bladder, so as 
to be entirely excluded from the general cavity, and there- 
fore had not produced any of the common symptoms of stone. 
I have seen in the same bladder, two, three, and even four 
such cysts, each containing a calculus of the size of a walnut. 
It is a circumstance deserving notice, that in the case, which 
gave celebrity to Mrs. Stevens’s medicine, and procured her 
a remuneration from Parliament, the bladder was not ex- 
amined after death. 
That calculi in the bladder do sometimes increase, while the 
patient is using alkaline medicines, is fully proved by the 
following examples, which also shew that the uric acid and 
phosphates are formed in different proportions, according to 
the peculiarities of the constitution , 
A gentleman who suffered from symptoms of stone was 
