ITS DIFFERENT PHASES OF DEVELOPMENT IN THE ANIMAL SERIES. 75 
74. Professors H. Nasse*, Schultz f- and Henle;};, who appear to have observed 
the nucleated cell of the fully-formed maminiferous blood both in its uncoloured and 
coloured stages as above described, have supposed it to be the “ red corpuscle” in 
such a stage. But its larger size (compare figs. 13 and 20, 14 and 23, 11 and 24) 
seems to forbid such a supposition. Supposing however that this objection could be 
waived, still it is nothing but unsupported conjecture to say that the nucleated cell 
and the “ red corpuscle” are exactly the same body in different, stages of development. 
75. On the other hand, there is a chain of evidence which appears to me to point 
forcibly to a different view of the nature of the “red corpuscle” of the fully-formed 
blood of Man and the Mammifera, whilst by implication it as forcibly forbids the 
supposition that the nucleated cell and “ red corpuscle” are exactly the same body — 
the latter the same as the former, only minus its nucleus, and with an increase of 
colour. 
76. The view of the nature of the “ red corpuscle” of the fully-formed blood of 
Man and the Mammifera to which I refer is this : the “ red corpuscle” of the fully- 
formed blood of Man and the Mammifera is the cellaefonn nucleus of the nucleated 
cell set free by the bursting of this cell itself, and become filled and red by the secre- 
tion of globuline and colouring matter into its interior ; and the chain of evidence 
which appears to me so forcibly to point to it is the following: — 
77. 1 st. Correspondence in Size between the Cellceform Nucleus of the Nucleated Cell 
and the “ Red Corpuscle." — Whilst, as we have seen, there is a marked difference in size 
between the nucleated cell and the “red corpuscle” of the same blood, there is on 
the contrary a striking correspondence in size between the cellseform nucleus of the 
nucleated cell and the “ red corpuscle.” A glance at the figures will show this. In 
human blood, in which the “ red corpuscle” is large, the cellseform nucleus of the 
nucleated cell is large. In the blood of the Horse, in which the “red corpuscle” is 
less, the cellseform nucleus of the nucleated cell is also less. Again, in Sheep’s blood, 
in which the “red corpuscle” is still less, the cellseform nucleus of the nucleated cell 
is still less. 
78. These facts, and the fact already pointed out by Mr. Gulliver, that the nucleus 
ofthe red nucleated corpuscle of the blood of the early inammiferous embryo is about 
the same size as the “ red corpuscles” in the same blood, which are similar to those of 
the fully-formed blood of the animal, were sufficient to draw my attention to the 
correspondence in size between the cellseform nucleus of the nucleated cell and the 
“ red corpuscle,” but not sufficient to satisfy me that it was more than a coincidence. 
I therefore became desirous of testing further the correspondence; and for this 
purpose it occurred to me that the blood of the Elephant (in which the “ red cor- 
puscles” are larger than those of any inammiferous animal, as Mr. Gulliver has 
* Article “Lymphe,” Wagner’s Handworterbuch. The blood referred to by Nasse was that of pregnant 
women especially. 
f Muller’s Archiv, 1839, p. 252. The blood examined was that of the Elephant. 
+ Algemeine Anatomie, p. 444, PI. IV. fig. 1 E. c. The blood referred to appears to be human blood. 
