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INTRODUCTION 
In April 1941 the Bureau of Entomology and Plant Quarantine issued 
E-557, A Review of Information on Anabasine, and in March 1942 E-561, A 
Review of Information on Nornicotine. These reviewed 163 and 50 publica- 
tions, respectively. The purpose of the present publication is to bring 
up to date all available information on both these promising insecticides* 
In preparing this review the following abstract journals, published 
from 1938 to 1943, inclusive, were searched: Biological Abstraots, Chemi- 
cal Abstracts, Chemisohes Zentralblatt, Experiment Station Record, Index 
Medious, and Review of Applied Entomology (Series A and B)« In addition 
the Quarterly Bibliography on Insectioide Materials of Vegetable Origin 
through No. 26 (January to March 1944), issued by the [Great Britain] 
Imperial Institute Consultative Committee on' Insectioide Materials of 
Vegetable Origin, -was consulted. 
CHEMISTRY OF ANABASINE 
The following constants for anabasine are given: Boiling point (p = 
238 mm.) 280.9° C, freezing point 9°, specifio rotation -83. 1© . Its 
parachor ooincides closely with the theoretical parachor.— Sokolov (75) . 
In a report on the reactions of amino-N-methylanabasines the follow- 
ing melting points are given: 
° C. 
alpha- Amino-N-methyl anabasine 95 - 95.3 
Derivatives: 
Aoetyl ~ — — 72 - 73 
Di acetyl, hydrate — — — 60.5- 62.5 
alpha f -Amino-N-nethylanabasine 91.5- 92.3 
Derivatives: 
Aeety} — — » _ ■ ■ ■■■■ 122 - 122*5 
Propionyl — — — — — 97 - 98 
Benzoyl ~— -— — — -— — 104 - 106 
Dibenzoyl — — — 142 - 143 
The picrate of the alpha compound decomposes at 238-239.5°, and that of 
the alpha 1 compound at 227.5-228°. The boiling point of the diaoetyl 
derivative is 160-162° (p=4 mm.), and that of propionyl derivative 
(p «5.5 mm.) 193-200°.— Kabachnik and JCitser (32). 
The dihydrochloride of dichloroanabasine is obtained by passing 
chlorine into anabasine in cold alcohol. The yield is 29-63 percent. 
It melts at 203.7°U. (dec.) Free dichloroanabasine dissolves in water 
with difficulty, is soluble in ethyl aloohol, slightly less soluble in 
ether, and melts at 51-3°. It reacts with picrio aoid, forming a picratt, 
