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tiients other than rotenone and since it has "been found that 
all of the active constituents of derris root or cube root 
can he extracted with ethyl ether, no objection is raised 
to considering this ethyl ether extract, known as "derris 
resins" or "cube resins," as the active ingredient of derris 
or cube preparations." 
The United States Department of Agriculture, Food and Drug 
Administration (427), on February 8, 1938, issued the following ruling 
on the labeling of derris and cube powders and other rotenone-bearing 
insecticides. 
Derris root powder and cube root powder are inherently insecti- 
cides. Derris contains as active ingredients rotenone and certain 
other compounds, such as toxicarol, tephrosin, and deguelin, and cube 
contains, in addition to rotenone, tephrosin and deguelin, as well as 
others. In the absence of practical methods for determining the per- 
centages of these constituents, other than rotenone, and since all of 
these active ingredients are soluble in ethyl ether, no objection has 
been raised to considering all of that portion of the root which is 
soluble in ethyl ether as active and designating it "derris resins" 
or "cube resins", as the case may be. The root fiber which is not 
soluble in ethyl ether is inert. For derris root powder, the following 
form of ingredient statement, which should appear upon the front or 
main panel of the label, is acceptable: 
ACTIVE INGREDIENT 
Derris resins $ 
INERT INGREDIENTS i 
P 
TOTAL 100$ 
the correct values being inserted in the blank spaces where indicated. 
A similar form of statement may be used for cube root powder, substi- 
tuting the percentage of cube resins for that of derris resins. It 
does not fulfil the requirements of the law to state "Derris and/or 
cube resins", since a statement of this character does not definitely 
specify the active ingredient. 
ROTENONE: In enforcing the I n secticide Act, the Administration 
has not required that the percentage of rotenone be stated on the label 
of derris root powder or cube root powder. However, owing to the 
trade practice of selling on the basis of rotenone content, manufacturers 
frequently desire to make such a statement on their labels and no 
objection is raised to this procedure, provided the value given is 
correct. It should be in terms of percentage of pure rotenone and not 
"Crude rotenone", which contains considerable amounts of impurities. 
The following forms of ingredient statement may be used: 
