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Barnett (15) in 1935 reported A. S. Small, High Commissioner 
for the Malay States, as referring to cube root as an important rival 
of derris. 
Faloon (137) in an article entitled "Is Eotenone Poisonous?" 
refers to derris and cube powders "being diluted with talc to a rotenone 
content of 0.75 or 1 percent rotenone. "Scientific tests have "been 
made to determine the residue left on apples after a thorough dusting 
with pure ground cube root — dust that analyzed four percent rotenone. 
It was found that the apples analyzed six one-hundredth s (6/l00ths) 
of a grain of cube dust per pound of apples. Inasmuch as the rotenone 
represented only four percent of the total dust applied, it is self- 
evident that the actual rotenone residue would be infinitesimal." 
Crilley (103) in 1936 reported the use of cube in Peru for curing 
mange, as a remedy for certain skin diseases, and for killing lice. 
Stoddard (397) in 1937 discussed the growing trend toward derris, 
cube, end pyrethrum in the use of agricultural insecticides. 
"The surface has hardly been scratched as yet. 
Derris and cube have possibilities which have only been 
lightly touched. Better and more effective methods of 
using them will open up new fields. * * * The older 
insecticide industry was based on a few insecticides of the 
heavy chemical type, requiring extensive equipment and 
large capital investment for their economical production. 
Derris, cube and pyrethrum as raw materials require no 
investment on the part of the insecticide manufacturer 
for their production and the investment required in the 
equipment necessary to convert them into the varied types 
of finished insecticides which can be made from them is 
small in proportion to the production and probably within 
the means of the average small company which is adequately 
financed." 
In an account of the translation of derris constituents in bean 
plants Fulton and Mason (157) in 1937 mentioned thpt observation of 
the use of cube as an insecticide showed similar phenomena. 
Nabuco de Araujo (291) in November 1936 and again (293) on 
March 10, 1937, reported on household insecticides marketed in Brazil. 
Recently various manufacturers of household insecticides have recom- 
mended the addition of small amounts of rotenone to the pyrethrum 
extracts. The rotenone extract used in Brazil is obtained from Timbo 
root, which is found in several places in this country, especially 
in the State of Para. Timbo root is also exported to the United 
States and several European countries. 
The United States Department of Agriculture, Food and Drug 
Administration (420), in its annual report for 1936, called attention 
to the rapid development of plant insecticides, such as those contain- 
ing derris, cube, pyrethrum extracts, and synthetic organic preparations, 
