-41- 
Preston ( 123 ) in 1935 reported as follows on the use of cube: 
In. experiments in Peru a suspension of the ground dried 
roots of cube ( jLoncho carpus ] in a solution of sodium' carbonate 
proved a successful dip in control" of ticks and mange mites on 
sheep. The treatment protected sheer) from reinf estetion with 
ticks for at least a. week. Ticks survived for several days on 
a piece of fleece wetted with the liquid and kept' moist, hut 
died in a day on another piece of fleece similarly wetted but 
allowed to dry. It is, therefore, concluded that the drying 
of the wool and the body warmth assist the action 'of the 
poison. The amount of sodium carbonate must be varied accord- 
ing to the hardness of the water. Two applications, Vith a 
week's interval, of a mixture of 1 t>art of cube powder and 100 
parts of oil cured mange on llamas. 
¥illiams ( 168 ) in 1934 reported that the latex from the roots of Lon- 
■cho carpus" nicou is used in the Andean highlands as a wash to kill ticks on 
cattle. ■ • "' * • " ' ; 
Meyer ( 102 ) in 1938 described the treatment of animals afflicted with 
scab by the use of timbo. A severe outbreak of scab among rabbits led to 
a trial of the toxic principle of timbo. The favorable results obtained led 
subsequently to the application of this substance in the treatment of various 
types of the disease in dogs, cats, swine, and other animals. A great 
improvement of the condition, and in many cases a complete cure, w a s obtained. 
The preparation used in the treatment of rabbits was an ointment made of 200 
gm, of powdered timbo roots, extracted in 2 liters of ether for 2 days. Two 
•hundred cc. of this solution was mixed with 1kg. of vaseline, which produced 
an ointment slightly yellow in color. ' The 'application of this ointment was 
found to be ^referable to wa.shing, because it left the'fur in better con- 
dition. On the other hanu, do^s, cats, and swine were treated with a liquid 
solution of 400 gm. of the powdered roots dissolved in 1 liter of 95-percent 
•alcohol, or 200 cc. of ethereal extract diluted in 800 cc,' of 95-percent 
alcohol. Incidentally, with the treatment of the' scab infection, a large 
proportion of the insect pests and ticks affecting these animals at the same 
time were destroyed. 
Literature 8ited 
•1.- ANONYMOUS 
1930. Powdered derris root. Pharm. 'Jour, and Pharm. (London] 
124: 568. 
2. 
1937. Long Ashton Research Station. Nature {jLondonJ 139:874-875. 
Noted in the Daily Digest, U.S. Dept. Agr. , 65 (53): 2. 
