16,6 Haughwout et al.: Protozoal Dysentery 639 
Pathological changes were noted also in the heart, spleen, 
liver, and kidneys, which, so far as we can determine, seemed 
to bear no relation to the balantidial infection. 
The alimentary tract was examined with particular care. 
Faecal material was taken from points along the lumen of the 
intestinal tract, promptly fixed, and later examined for balan- 
tidia. None was found. The small intestine showed a slight 
thinning of the mucosa, and a marked thinning of the entire 
wall. The large intestine showed some oedema and slight in- 
duration of the wall which, at the points of flexure, was 
thickened. This thickening was slight in extent and was most 
marked in the sigmoid colon near the caecum in the region of 
the splenic flexure. At this point the intestinal wall was thicker, 
rougher, and more congested than the rest of the gut and 
showed petechial haemorrhages. It was firm in consistence. 
Here the mucosa was slightly congested and dirty looking. 
There was evidence of an increase of the mucous secretion and 
of epithelial desquamation. No ulceration of any kind was 
noted m.acroscopically in any portion of the gut. The anatom- 
ical diagnosis was : Toxaemia, acute vegetative septicaemia, 
aortic endocarditis, abscess of the base of the left lung with 
fibrino-purulent pleurisy, acute bronchopneumonia of the base 
of the right lung, fatty degeneration of the viscera, chronic ca- 
tarrhal colitis, and haemorrhagic infarction of the spleen. 
The area of the large intestine that had been the site of the 
healed colitis was excised and divided between the two opera- 
tors. That taken by the pathologist was fixed in Zenker’s fluid ; 
that taken by the senior author was fixed in Bouin’s picro-aceto- 
formol fluid. Pieces were similarly cut from the ileum near 
the ileo-caecal valve and from the duodenum, divided and fixed 
similary. Blocks cut from the other viscera were fixed in Zen- 
ker’s fluid. 
After thorough washing out of the fixing fluid, the intestine 
was cut into many small pieces. These were embedded and 
sectioned. We fully expected to find balantidia in the intestinal 
tissues, notwithstanding we had failed to find them in the 
lumen of the bowel, and when sections from the first few blocks 
failed to yield any, we were at first mildly interested ; but when 
we had cut and stained three to five sections from each block 
of the Bouin-fixed tissue, and had utterly failed to find any 
parasites, our interest was thoroughly aroused. More sections 
