INTIiODUCTIOK 
Anatasine is a liquid alkaloid vihich closely rese!n"bles nicotine in 
its physical, cherni cjal. , pharmacological, and insecticidal properties. It 
is soluble in wate- in all proportions and is less volatile than nicotine 
Anatasine has the r^olecular formula Cio%4^'2 ancL the follovrins structural 
formula: 
H 
Hj- C 
'\ 
H- C 
H- C C - H 
%^ 
C - H2 
C-H C - K2 
Hg-C 
C- He 
H 
A. 
H - C' "C C^ -C- H2 
i 
H - C C-H 
CH 
AN ABAS IN 
NICOTINE 
The structural formula of nicotine is shown for comparison, and it 
is evident that no other possible pyridyl-piperidine so closely resembles 
nicotine as does anabasine , which chemically is beta-pyridyl-alpha- 
piperidine. 
The principal physical constants of anabasine are as follows: 
Anabasine is a colorless, somewhat viscous liquid which turns brown 
on standing in contact with air. It is very stable, appreciably basic in 
reaction, and forms salts in typical alkaloidal fashion. 
The odor of anabasine resembles that of nicotine but is less intense. 
Solubility: Soluble in water in all proportions. Nicotine i-s sol^lblt 
in water in all proportions only below 60^. Anabasine is also soluble in 
all organic solvents. 
Specific gravity : 20/20 1.0481 (Nelson, 85) 
Boiling point ; 280.9° at 760 mm. (Nelson, 85) 
Refractive index : 20 1.5443 (Nelson, 85) 
Optical rotation: [alpha]^ -59.66 (Nelson, 85) 
