35 
Summary . — The results of the above experiments may be summar- 
ized as follows: 
Thyroid. 
Gm. 
thyroid fed 
daily. 
Percentage 
of iodine 
in thyroid. 
Fatal dose of aceto- 
nitrile in mgms. 
per gm. 
Recovered. 
Died. 
A. Children’s 
0.05 
0 
1.4 
B. Controls 
0.3 
Unfortunately the experiments were not sufficiently numerous for 
the fatal doses to be determined, but it is evident that the children’s 
thyroid had protected the mice against at least five times the dose of 
acetonitrile fatal to the controls. 
Series II. 
A. CHILDREN’S THYROID; IODINE FREE. 
Date. 
Weight of 
mouse. 
1906. 
1 
July 28 
20.51 
30 
20.40 
August 3 
19.00 
7 
16.80 
9 
15. 69 
July 28 
21.63 
30 
20. 96 
August 3 
21.00 
7 
19.00 
9 „ 
18.50 
10 
18.50 
Remarks. 
i 
Feeding of cakes each containing 0.05 gm. thyroid begun. 
Acetonitrile, 31.38 mgms., i. e., 2 mgms. per gm. mouse. Survived. 
Thyroid as above. 
! Acetonitrile, 38.85 mgms., i. e., 2.1 mgms. per gm. mouse. Died 1J hours. 
B. SHEEP THYROID; 0.176 PER CENT IODINE. 
1906. 
July 28 
23. 71 
30 
22.79 
August 3 
20.39 
7 
17.91 
July 28 
24.52 
30 
21.14 
August 3 
19.00 
7 
15. 70 
8 
15.25 
July 28 
15.81 
30 
16.53 
August 3 
16.56 
7 
17.50 
9 
14.33 
July 28 
14.11 
30 
14.36 
August 3 
14. 08 
4 
12.78 
9 
12. 41 
Feeding of cakes each containing 0.05 gm. thyroid begun. 
Acetonitrile, 25.07 mgms., i. e., 1.4 mgms. per gm. mouse. Survived. 
Thyroid as above. 
Acetonitrile, 30.5 mgms., i. e., 2 mgms. per gm. mouse. Survived. 
Thyroid as above. 
Acetonitrile, 32.96 mgms., i. e., 2.3 mgms. per gm. mouse. Died If hours. ' 
Thyroid as above. 
Acetonitrile, 32.27 mgms., i. e., 2.6 mgms. per gm. mouse. Died 2 hours. 
