36 
C. CONTROLS. 
Date. Remarks, 
mouse. | 
1906, 
Jiilv 28. . 22.42 Cakes without thvroid 
‘ 30. ....... . 23. 51 
August 3. . 24 70 
7. . .... . 22. 83 
8. . ... _ 21. 91 Acetonitrile, 3.07 mgms., i. e., 0.14 mgm. per gm. mouse. Survived. 
Julv 28. ....... . 27. 6S Cakes without thvroid. 
‘30,.. 28.02 1 
August 3 28.73 ! 
7 27. 04 
9. 24 61 Acetonitrile, 418 mgms., i. e., 0.17 mgm. per gm. mouse. Survived. 
July 28 22.33 Cakes without thvroid. 
* 30 21.62 1 
August 3 21. 11 
7 18. 42 
8 17.58 Acetonitrile, 3.52 mgms., i. e., 0.20 mgm. per gm. mouse. Died 1 to 2 hours. 
July 28 21. 85 Cakes without thvroid. 
‘30 22. 30 
August 3 22.06 
7 20. 77 Acetonitrile, 5.19 mgms. , i. e., 0.25 mgm. per gm. mouse. Died If hours. 
Summary . — The results of the above experiments may be summar- 
ized as follows : 
Thyroid. 
A. Children’s. 
B. Sheep 
C. Controls... 
Gm. 
thyroid fed 
daily. 
Percentage 
of iodine 
in thyroid. 
Mgm. I 
in thvroid 
fed. 
0.05 
. 05 
0 
.176 
0 
.088 
Fatal dose of aceto- 
nitrile in mgms. 
per gm. 
Recovered. Died. 
2. 0 2. 1 
2. 0 2. 3 
.17 .2 
In these experiments both the children's and sheep’s thyroids pro- 
tected against ten times the fatal dose of acetonitrile; the iodine free 
children's thyroids were as effective as the iodine containing sheep’s 
thyroids. But, as appears from the following experiments, too 
much thyroid had been given to admit of comparison — that is, the 
maximum effect had been produced in each case. 
In the next series smaller amounts of children’s thyroid were fed 
and the results compared with those obtained with guinea pig’s 
thyroid; the latter contained 0.05 per cent iodine. 
