54 
C. CONTROLS. 
Date. 
Weight 
of mouse. 
Remarks. 
1907. 
November 22... 
20.03 
Feeding of cakes without thyroid begun. 
26... 
20. 17 
29... 
19.85 
December 2... 
19.30 
Acetonitrile, 7.33 mgms., i. e., 0.38 mgm. per gm. mouse. Survived. 
November 22... 
21.38 
Cakes as above. 
26... 
20.00 
29... 
20.26 
December 2 . . . 
19. 07 
3... 
18.86 
Acetonitrile, 8.11 mgms., i. e., 0.43 mgm. per gm. mouse. Survived. 
November 22... 
22.67 
Cakes as above. 
26... 
20.40 
29... 
19.44 
December 2... 
19.30 
Acetonitrile, 8.69 mgms., i. e., 0.45 mgm. per gm. mouse. Died 4 hours. 
November 22... 
23.63 
Cakes as above. 
26... 
22.89 
29...; 
21.65 
December 2... 
21.96 
3...; 
22.32 
4 ' 
22.43 
Acetonitrile, 10.54 mgms., i. e., 0.47 mgm. per gm. mouse. Died 2 hours. 
Summary . — The results of the above experiments may be summa- 
rized as follows: 
Gm. thy- 
roid fed 
daily. 
Percentage 
of iodine 
; in thyroid. 
Mgm. I in 
thvroid fed 
daily. 
Fatal dose of aceto- 
nitrile in mgms. 
per gm. 
Recovered. 
Died. 
A | 
B 
C. Controls 
0.005 
.005 
0.087 
.170 
0. 00435 
.0085 
1.8 
3. 5 
.43 
2.0 
4.0 
.45 
The thyroid with approximately twice the amount of iodine pro- 
tected against approximately twice the^ dose of acetonitrile. 
