25 
Summary . — The results of these experiments may be tabulated 
as follows: 
Gm. 
thyroid 
fed daily. 
Mgm. I in 
thyroid. 
Weight of 
mouse in 
gms. 
Amount of acetonitrile 
in mgms. 
Result. 
Per mouse. 
Per gm. 
mouse. 
A 
0.001 
0.0019 
14.74 
67.8 
4.6 
Survived. 
.001 
.0019 
14.40 
71. 12 
4.8 
Died. 
B 
0 
0 
12.64 
5.06 
.4 
Survived. 
0 
0 
12.04 
5.06 
.42 
Died. 
The mouse which had received the thyroid recovered from about 
eleven times the dose fatal to the controls. A total of less than 
10 mgms. of thyroid had enabled the mouse to neutralize about 
61.8 mgms. acetonitrile. 
Series IV. 
A. SHEEP THYROID; 0.32 PER CENT IODINE. 
Date. 
Weight 
of mouse. 
Remarks. 
1908. 
April 28 
18.10 
19. 22 
18. 91 
18. 91 
13.48 
14.58 
15.03 
Feeding of cakes, each containing 0.0005 gm. thyroid, begun. 
Acetonitrile, 62.40 mgms., i. e., 3.3 mgms. per gm. mouse. Survived. 
Thyroid as above. 
Acetonitrile, 52.60 mgms., i. e., 3.5 mgms. per gm. mouse. Died 6J hours. 
May 2 
7 
8 
April 28 
May 2 
7 
B. CONTROLS. 
1908. 
April 28 
18.98 
Feeding of cakes without thyroid begun. 
May 2 
7 
8 
20. 34 
19.53 
Acetonitrile, 10.94 mgms., i. e., 0.56 mgm. per gm. mouse. Survived. 
Cakes as above. 
April 28.. » 
19. 04 
May 2 
7 
8 
20.63 
18.83 
j Acetonitrile, 10.92 mgms., i. e., 0.58 mgm. per gm. mouse. Died 7 hours. 
Summary . — The results of these experiments may be tabulated 
as follows: 
Gm. 
thyroid fed 
daily. 
Mgm. I in 
thyroid. 
Weight of 
mouse in 
gms. 
Amount of acetonitrile 
in mgms. 
Result. 
Per mouse. 
Per gm. 
mouse. 
A 
0. 0005 
0.0016 
18.91 
62.4 
3.3 
Survived. 
.0005 
.0016 
15.03 
52.6 
3.5 
Died. 
E 
0 
0 
19.53 
10.94 
.56 
Survived. 
0 
0 
18.83 
10.92 
.58 
Died. 
