68 
F. THYRADEN (B); 0.085 PER CENT IODINE. 
Date. 
Weight of 
mouse. 
1908. 
July 3 
12.98 
9 
12. 42 
11 
11.78 
12 
July 3 
14. 07 
9 
12.72 
11 
12.77 
12 
July 3 
14. 56 
9 
13. 80 
11 
13. 27 
12 
July 3 
16.24 
9 
13. 80 
11 
13.60 
Remarks. 
Feeding of cakes each containing 0.002 gm. thyraden commenced. 
Acetonitrile, 12.96 mgms., i. e., 1.1 mgms. per gm. mouse. Survived. 
Thyraden as above. 
Acetonitrile, 16.6 mgms., i. e., 1.3 mgms. per gm. mouse. Survived. 
Thyraden as above. 
Acetonitrile, 18.57 mgms., i. e., 1.4 mgms. per gm. mouse. Died 2| hours. 
Thyraden as above. 
Acetonitrile, 20.40 mgms., i. e., 1.5 mgms. per gm. mouse. Died 3} hours. 
G. CONTROLS. 
1908. 
July 3 
18. 24 
9 
14. 45 
10 
July 3 J. 
15.08 
9 
13. 50 
11 
13. 50 
13 
12.95 
July 3 
15. 89 
9 
13.40 
11 
13. 50 
July 3 
18.08 
9 
17. 07 
11 
17.63 
12 
July 3 
16. 04 
9 
14. 12 
11 
14.86 
12 
Feeding oi cakes without thyroid commenced. 
Acetonitrile, 3.03 mgms., i. e., 0.21 mgm. per gm. mouse. Survived. 
Cakes as above. 
Acetonitrile, 3.5 mgms., i. e., 0.27 mgm. per gm. mouse. Survived. 
Cakes as above. 
Acetonitrile, 4.05 mgms., i. e., 0.3 mgm. per gm. mouse. Survived. 
Cakes as above. 
Acetonitrile, 5.47 mgms., i. e., 0.31 mgm. per gm. mouse. Died 4h hours. 
Cakes as above. 
Acetonitrile, 5.05 mgms., i. e., 0.34 mgm. per gm. mouse. Died 3J hours. 
SUMMARY. 
Gm. 
thyroid 
fed daily. 
Percentage 
of iodine 
in thyroid. 
Mgm. I in 
thyroid 
fed daily. 
Fatal dose of ace- 
tonitrile in mgms. 
per gm. 
Recovered. 
Died. 
A. 1 
0.001 
0.085 
0. 00085 
0.66 
0.75 
B 
.001 
.085 
.00085 
.50 
.55 
C 
.001 
.092 
.00092 
.45 
.6 
D 
.0005 
.092 
. 00046 
.33 
.38 
E 
.002 
.085 
.00170 
1.2 
1.3 
F 
.002 
.085 
.00170 
1.3 
1.4 
G. Controls ' 
.3 
.31 
